Novel insights into hepatitis C virus replication and persistence

R Bartenschlager, M Frese… - Advances in virus …, 2004 - books.google.com
Proteolytic Processing of Structural Proteins Proteolytic Processing of Nonstructural Proteins
Cis-Acting RNA Sequences Required for Replication Mechanism of RNA Replication …

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

R Kittler, G Putz, L Pelletier, I Poser, AK Heninger… - Nature, 2004 - nature.com
RNA interference (RNAi) is an evolutionarily conserved defence mechanism whereby genes
are specifically silenced through degradation of messenger RNAs; this process is mediated …

Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages

A Iavarone, ER King, XM Dai, G Leone… - Nature, 2004 - nature.com
In mammals, the fetal liver is the first site of definitive erythropoiesis—the generation of
mature, enucleated red cells. The functional unit for definitive erythropoiesis is the …

Strategies for hepatitis C therapeutic intervention: now and next

SL Tan, Y He, Y Huang, M Gale Jr - Current opinion in pharmacology, 2004 - Elsevier
Interferon-α-based therapies are the mainstay of hepatitis C treatment. However, these
broad immunomodulatory agents, already limited by their side effects, expense and route of …

RNA interference–small RNAs effectively fight viral hepatitis

A Shlomai, Y Shaul - Liver International, 2004 - Wiley Online Library
RNA interference (RNAi) is the process of sequence‐specific gene silencing, initiated by
double‐stranded RNA that is homologous in sequence to the target gene. This unique …

Gene silencing with RNA interference: a novel tool for the study of physiology and pathophysiology of adrenal cortex

AS Barbosa, CJ Lin - Arquivos Brasileiros de Endocrinologia & …, 2004 - SciELO Brasil
A inativação de genes por knock-out ou por bloqueio da tradução de seus transcritos
(silenciamento) constitui uma estratégia extremamente poderosa tanto para atribuir função …

RNA 干扰在抗HCV, HBV 方面的研究进展

席晓蓉, 孙强明 - 国外医学: 病毒学分册, 2004 - cqvip.com
HCV, HBV 感染引起的慢性肝炎, 肝硬化, 肝癌已成为全世界关注的健康问题.
而防治这些严重肝病的关键仍是抗病毒治疗. RNA 干扰自发现以来, 已在病毒 …

Developments in effective application of small inhibitory RNA (siRNA) technology in mammalian cells

BG Cocks, TP Theriault - Drug Discovery Today: Targets, 2004 - Elsevier
siRNA technology provides a useful means of achieving reduction of gene expression in
mammalian cells. In this article we focus on recent advances that make siRNA technology …

[HTML][HTML] Silenciamento de genes com RNA interferência: um novo instrumento para investigação da fisiologia e fisiopatologia do córtex adrenal

AS Barbosa, CJ Lin - Arquivos Brasileiros de Endocrinologia & …, 2004 - SciELO Brasil
A inativação de genes por knock-out ou por bloqueio da tradução de seus transcritos
(silenciamento) constitui uma estratégia extremamente poderosa tanto para atribuir função …

[HTML][HTML] 短发夹RNA 抑制外源荧光素酶在肝癌细胞中的表达

胡礼仪, 张有顺, 周新, 戴宗晴, 黄玲, 王菊 - 世界华人消化杂志, 2004 - wjgnet.com
短发夹RNA抑制外源荧光素酶在肝癌细胞中的表达 主页 简体中文 English 简体中文 登录 BPG
Management System F6Publishing-Submit a Manuscript F6Publishing-世界华人消化杂志在线 …