▪ Abstract Chemokines compose a sophisticated communication system used by all our cell
types, including immune cells. Chemokine messages are decoded by specific receptors that …

The aim of this review is to give an overview of the role of chemokines, particularly ligands of
the CC chemokine receptor CCR3, in allergic diseases and to show the new concept in the …

Eliciting broadly neutralizing antibodies to human immunodeficiency virus could bring closer
the goal of a successful AIDS vaccine. Here the International AIDS Vaccine Initiative …

In a recent study, we demonstrated that glycosaminoglycan (GAG) binding and
oligomerization are essential for the in vivo function of the chemokines MCP-1/CCL2 …

A hallmark of autoimmunity and other chronic diseases is the overexpression of chemokines
resulting in a detrimental local accumulation of proinflammatory immune cells. Chemokines …

Human interferon-inducible protein 10 (IP-10; HGMW-approved gene symbol CXCL10) is an
ELR− CXC chemokine that contains binding domains for both the chemokine receptor …

Chemokines are small chemoattractant cytokines that control a wide variety of biological and
pathological processes, ranging from immunosurveillance to inflammation, and from viral …

The biological activity of chemokines requires interactions with cell surface proteoglycans.
We have determined the structure of the chemokine RANTES (regulated on activation …

Chemokine-mediated recruitment of leukocytes in vivo depends on interactions with cell
surface glycosaminoglycans. Lymphotactin, the unique member of the" C" chemokine …

The binding of proteins to glycosaminoglycans (GAGs) is the prerequisite for a large number
of cellular processes and regulatory events and is associated to many pathologies …