Asthma phenotypes in childhood: lessons from an epidemiological approach

RT Stein, FD Martinez - Paediatric respiratory reviews, 2004 - Elsevier
Asthma is a heterogenous disease with variable signs and symptoms among patients. It also
presents significant individual variability over time. Recently, some important population …

Developmental immunotoxicology of lead

RR Dietert, JE Lee, I Hussain, M Piepenbrink - Toxicology and applied …, 2004 - Elsevier
The heavy metal, lead, is a known developmental immunotoxicant that has been shown to
produce immune alterations in humans as well as other species. Unlike many compounds …

Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma

R Djukanovic, SJ Wilson, M Kraft… - American journal of …, 2004 - atsjournals.org
IgE plays an important role in allergic asthma. We hypothesized that reducing IgE in the
airway mucosa would reduce airway inflammation. Forty-five patients with mild to moderate …

Viral infections in relation to age, atopy, and season of admission among children hospitalized for wheezing

PW Heymann, HT Carper, DD Murphy… - Journal of allergy and …, 2004 - Elsevier
BACKGROUND: Viral respiratory tract infections and atopy are associated with attacks of
wheezing during childhood. However, information about the relationship between viral …

Childhood factors associated with asthma remission after 30 year follow up

JM Vonk, DS Postma, HM Boezen, MH Grol… - Thorax, 2004 - thorax.bmj.com
Background: Factors contributing to either “complete” or “clinical” remission of asthma are
important to know since there is no cure for the disease. Methods: A cohort of 119 allergic …

Relationship between socioeconomic status and asthma: a longitudinal cohort study

RJ Hancox, BJ Milne, DR Taylor, JM Greene… - Thorax, 2004 - thorax.bmj.com
Background: There is conflicting information about the relationship between asthma and
socioeconomic status, with different studies reporting no, positive, or inverse associations …

Change in prevalence of asthma in Danish children and adolescents

SF Thomsen, CS Ulrik, K Larsen, V Backer - Annals of allergy, asthma & …, 2004 - Elsevier
BACKGROUND: There is evidence suggesting that the prevalence of asthma has increased,
especially in industrialized countries. OBJECTIVE: To investigate whether the prevalence of …

Age-specific relationship between CD14 and atopy in a cohort assessed from age 8 to 25 years

AR O'Donnell, BG Toelle, GB Marks… - American journal of …, 2004 - atsjournals.org
CD14 influences postnatal switching of T helper cell responses. CD14 C− 159T has been
associated with altered CD14 and IgE levels in cross-sectional studies. Identifying whether …

[图书][B] Allergens and allergen immunotherapy

RF Lockey, SC Bukantz, J Bousquet - 2004 - api.taylorfrancis.com
As I look over my library, one book is the most battle-scarred and well-worn: It is Allergens
and Allergen Immunotherapy, the first edition published about 15 years ago. My partners …

Respiratory symptoms and lung function in relation to atopy in children born preterm

M Siltanen, E Savilahti, M Pohjavuori… - Pediatric …, 2004 - Wiley Online Library
Respiratory morbidity is a major health problem among children. The aim of this study was to
compare the background of respiratory problems of children born preterm with that of …