Fos, nociception and the dorsal horn

RE Coggeshall - Progress in neurobiology, 2005 - Elsevier
The protooncogene c-fos is rapidly activated after noxious stimuli to express the protein Fos
in spinal dorsal horn neurons that are in the 'correct'locations for nociceptive information …

Galanin and its receptors in neurological disorders

L Lundström, A Elmquist, T Bartfai, Ü Langel - Neuromolecular medicine, 2005 - Springer
Galanin is a highly inducible neuropeptide, showing distinct up-regulation after pathological
disturbance within the nervous system. Significant increase in galanin expression is …

Use of genetically engineered transgenic mice to investigate the role of galanin in the peripheral nervous system after injury

FE Holmes, SA Mahoney, D Wynick - Neuropeptides, 2005 - Elsevier
The neuropeptide galanin is present at high levels within the dorsal root ganglia (DRG) and
spinal cord during development and after peripheral nerve damage in the adult. This pattern …

Galanin and spinal nociceptive mechanisms: recent results from transgenic and knock-out models

Z Wiesenfeld-Hallin, XJ Xu, JN Crawley, T Hökfelt - Neuropeptides, 2005 - Elsevier
Genetically modified mice with transgenic overexpression of galanin or depletion of genes
for galanin or galanin receptors have become available, providing a new approach for …

Generation and phenotypic characterization of a galanin overexpressing mouse

K Holmberg, E Kuteeva, P Brumovsky, U Kahl… - Neuroscience, 2005 - Elsevier
In most parts of the peripheral nervous system galanin is expressed at very low levels. To
further understand the functional role of galanin, a mouse overexpressing galanin under the …

[125I]-Galanin binding in brain of wildtype, and galanin-and GalR1-knockout mice: strain and species differences in GalR1 density and distribution

SRF Jungnickel, AL Gundlach - Neuroscience, 2005 - Elsevier
Widespread production of knockout and transgenic mice has led to an increased use of mice
as animal models for studies of normal-and patho-physiology. Hence, the precise mapping …

Douleurs neuropathiques et inflammatoires: modèles animaux et rôles fonctionnels des neuropeptides

M Landry, F Nagy - Douleur et analgésie, 2005 - Springer
Chronic pain is associated with plastic changes responsible from a persitent sensitization in
the spinal cords. The studies of these changes have benefit substantially from the …

[引用][C] 甘丙肽及其受体在痛觉调控中的作用

安珂, 田玉科 - 国外医学: 麻醉学与复苏分册, 2005