DNA methylation and chromatin structure: the puzzling CpG islands

P Caiafa, M Zampieri - Journal of cellular biochemistry, 2005 - Wiley Online Library
DNA methylation is the epigenetic modification, which introduces 5mC as fifth base onto
DNA. As for the distribution of 5mCs, it is well known that they distribute themselves in a non …

DNA methylation and the expanding epigenetics of T cell lineage commitment

CB Wilson, KW Makar, M Shnyreva… - Seminars in immunology, 2005 - Elsevier
During their development from progenitors, lymphocytes make a series of cell fate decisions.
These decisions reflect and require changes in overall programs of gene expression. To …

Modulation of DNMT1 activity by ADP-ribose polymers

A Reale, GD Matteis, G Galleazzi, M Zampieri, P Caiafa - Oncogene, 2005 - nature.com
We provided evidence that competitive inhibition of poly (ADP-ribose) polymerases in
mammalian cells treated with 3-aminobenzamide causes DNA hypermethylation in the …

Silence of the genes—mechanisms of long-term repression

L Lande-Diner, H Cedar - Nature Reviews Genetics, 2005 - nature.com
A large fraction of genes in the mammalian genome is repressed in every cell throughout
development. Here, we propose that this long-term silencing is carried out by distinct …

DNA methylation in epigenetic control of gene expression

A Razin, B Kantor - Epigenetics and Chromatin, 2005 - Springer
Over three decades ago DNA methylation had been suggested to play a role in the
regulation of gene expression. This chapter reviews the development of this field of research …

Identification of SP5 as a downstream gene of the β-catenin/Tcf pathway and its enhanced expression in human colon cancer

M Takahashi, Y Nakamura… - … journal of oncology, 2005 - spandidos-publications.com
Abstract Mutations in APC, CTNNB1, AXIN1 or AXIN2 cause impairment in the β-catenin
degradation pathway and result in accumulation of β-catenin in a wide range of human …

Maintenance and regulation of DNA methylation patterns in mammals

Z Chen, AD Riggs - Biochemistry and cell biology, 2005 - cdnsciencepub.com
Proper establishment and faithful maintenance of epigenetic information is crucial for the
correct development of complex organisms. For mammals, it is now accepted that DNA …

DNA methylation, nucleosome formation and positioning

S Pennings, J Allan, CS Davey - Briefings in Functional …, 2005 - academic.oup.com
Recent mapping of nucleosome positioning on several long gene regions subject to DNA
methylation has identified instances of nucleosome repositioning by this base modification …

Patterned CpG methylation of silenced B cell gene promoters in classical Hodgkin lymphoma-derived and primary effusion lymphoma cell lines

JR Doerr, CS Malone, FM Fike, MS Gordon… - Journal of molecular …, 2005 - Elsevier
Hodgkin and Reed–Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL) and
primary effusion lymphoma (PEL) are derived from germinal center (GC) and post-GC B …

Transcriptional regulation of early transposon elements, an active family of mouse long terminal repeat retrotransposons

IA Maksakova, DL Mager - Journal of virology, 2005 - Am Soc Microbiol
While early transposon (ETn) endogenous retrovirus (ERV)-like elements are known to be
active insertional mutagens in the mouse, little is known about their transcriptional …