Purpose Older patients are significantly underrepresented in cancer clinical trials. A
literature review was undertaken to identify the barriers that impede the accrual of this …

Abstract Learning Objectives After completing this course, the reader will be able to: Discuss
the implications of age bias in clinical trials. Describe the effects of applying clinical trial …

The best treatment for elderly patients with advanced non–small-cell lung cancer (NSCLC)
is still debated. To guide clinical management of these patients and suggest the priorities for …

BACKGROUND Older women, and older minorities in particular, are under represented in
breast cancer trials. Although socioeconomic status (SES) is associated with both race and …

Purpose To determine the tolerability of capecitabine in elderly patients with advanced
colorectal cancer (CRC). Patients and Methods Fifty-one patients with advanced CRC who …

Purpose Older patients are underrepresented in many areas of cancer services utilization
and in clinical trial enrollment. This study evaluates whether age, when adjusted for sex …

Purpose To design and test a geriatric educational intervention to improve accrual of cancer
patients age 65 years and older to cooperative group–sponsored treatment trials. Methods …

METHODS This study was a project of the Cancer Research Network, a consortium of 11
health plans funded by the National Cancer Institute (NCI). Cancer Research Network plans …

OBJECTIVE.: Elderly patients are less likely to receive surgery and platinum-based
combination chemotherapy than younger patients. We evaluated multi-institutional …

The adverse consequences of comorbidity pose a major clinical challenge in the care of
older cancer patients. While the burden of comorbidity is clearly a major prognostic factor for …