Cytokine release from alveolar macrophages exposed to ambient particulate matter: heterogeneity in relation to size, city and season

RB Hetland, FR Cassee, M Låg, M Refsnes… - Particle and fibre …, 2005 - Springer
Background Several studies have demonstrated an association between exposure to
ambient particulate matter (PM) and respiratory and cardiovascular diseases. Inflammation …

Activation of the aryl hydrocarbon receptor increases pulmonary neutrophilia and diminishes host resistance to influenza A virus

S Teske, AA Bohn, JF Regal… - … of Physiology-Lung …, 2005 - journals.physiology.org
Unlike their role in bacterial infection, less is known about the role of neutrophils during
pulmonary viral infection. Exposure to pollutant 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin …

Benzo [a] pyrene, but not 2, 3, 7, 8-TCDD, induces G2/M cell cycle arrest, p21CIP1 and p53 phosphorylation in human choriocarcinoma JEG-3 cells: a distinct …

JS Drukteinis, T Medrano, EA Ablordeppey… - Placenta, 2005 - Elsevier
Maternal cigarette smoking is known to disrupt placental growth and function. The
polyaromatic hydrocarbon benzo [a] pyrene (BaP) is a major toxicant in cigarette smoke that …

Role of cell signaling in B [a] P-induced apoptosis: characterization of unspecific effects of cell signaling inhibitors and apoptotic effects of B [a] P metabolites

A Solhaug, S Øvrebø, S Mollerup, M Låg… - Chemico-biological …, 2005 - Elsevier
Here we show that several cell signaling inhibitors have effect on cyp1a1 expression and
the metabolism of benzo [a] pyrene (B [a] P) in Hepa1c1c7 cells. The CYP1A1 inhibitor α …

Human CD34-positive hematopoietic stem cells constitute targets for carcinogenic polycyclic aromatic hydrocarbons

J van Grevenynghe, M Bernard, S Langouet… - … of Pharmacology and …, 2005 - ASPET
Polycyclic aromatic hydrocarbons (PAHs) are major carcinogenic environmental
contaminants known to exert bone marrow toxicity and to induce leukemias, suggesting that …

[HTML][HTML] Studies on health effects of transport-related air pollution

J Heinrich, PE Schwarze, N Stilianakis… - Health effects of …, 2005 - books.google.com
Often, the effects observed in epidemiological studies cannot be attributed to the specific
indicators addressed, but to a mixture of pollutants. Fine PM (including black smoke) and …

Valinomycin-induced apoptosis of human NK cells is predominantly caspase independent

A Paananen, K Järvinen, T Sareneva… - Toxicology, 2005 - Elsevier
Human NK cells are sensitive to the exogenous toxic compound valinomycin. This toxin,
produced by Streptomyces griseus in moisture damaged buildings, induces apoptosis by …

Effects of diesel exhaust particle extracts and some of the major nitrated polycyclic aromatic hydrocarbon components on apoptotic and cell signalling in Hepa1c1c7 …

NE Landvik - 2005 - duo.uio.no
Polycyclic aromatic hydrocarbons (PAH) are environmental pollutants formed during
incomplete combustion of organic material. They are present in many mixtures such as …