Toward an understanding of NKT cell biology: progress and paradoxes
M Kronenberg - Annu. Rev. Immunol., 2005 - annualreviews.org
▪ Abstract Natural killer T (NKT) cells constitute a conserved T cell sublineage with unique
properties, including reactivity for a synthetic glycolipid presented by CD1d, expression of an …
properties, including reactivity for a synthetic glycolipid presented by CD1d, expression of an …
Isosteric replacement of sulfur with other chalcogens in peptides and proteins
L Moroder - Journal of peptide science: an official publication of …, 2005 - Wiley Online Library
The review addresses the functional and structural properties of the two series of chalcogen
analogues of amino acids in peptides and proteins, the methionine and the serine/cysteine …
analogues of amino acids in peptides and proteins, the methionine and the serine/cysteine …
The crystal structure of human CD1d with and without α-galactosylceramide
M Koch, VS Stronge, D Shepherd, SD Gadola… - Nature …, 2005 - nature.com
The glycolipid α-galactosylceramide binds with high affinity to CD1d and stimulates natural
killer T cells. Here we report the crystal structure of human CD1d in complex with synthetic α …
killer T cells. Here we report the crystal structure of human CD1d in complex with synthetic α …
Peripheral blood IFN‐γ‐secreting Vα24+Vβ11+ NKT cell numbers are decreased in cancer patients independent of tumor type or tumor load
JW Molling, W Kölgen, HJJ van der Vliet… - … journal of cancer, 2005 - Wiley Online Library
Natural killer T (NKT) cells are CD1d‐restricted lymphoid cells and are characterized by an
invariant T‐cell receptor, which in humans consists of a Vα24 chain paired with a Vβ11 …
invariant T‐cell receptor, which in humans consists of a Vα24 chain paired with a Vβ11 …
Anatomy of CD1–lipid antigen complexes
DB Moody, DM Zajonc, IA Wilson - Nature Reviews Immunology, 2005 - nature.com
CD1 proteins bind lipids to form antigen complexes that contact T-cell receptors and activate
T cells. Recent crystal structures of CD1 proteins show that their antigen-binding grooves …
T cells. Recent crystal structures of CD1 proteins show that their antigen-binding grooves …
Deficiency of a subset of T-cells with immunoregulatory properties in sarcoidosis
Background Sarcoidosis is a multisystem disorder that predominantly involves the lungs,
characterised by a T-helper 1 (Th1) biased CD4-positive T-cell response and granuloma …
characterised by a T-helper 1 (Th1) biased CD4-positive T-cell response and granuloma …
Circulating Vα24+ Vβ11+ NKT cell numbers and dendritic cell CD1d expression in hepatitis C virus infected patients
HJJ van der Vliet, JW Molling, BME von Blomberg… - Clinical …, 2005 - Elsevier
CD1d-restricted natural killer T (NKT) cells are involved in the regulation of various immune
responses, and have been shown to inhibit viral replication in animal hepatitis models when …
responses, and have been shown to inhibit viral replication in animal hepatitis models when …
iNKT-cell responses to glycolipids
VV Parekh, MT Wilson… - Critical Reviews™ in …, 2005 - dl.begellhouse.com
Invariant natural killer T (iNKT) cells are an unusual group of T lymphocytes that recognize
glycolipid antigens presented by the major histocompatibility complex class I-related protein …
glycolipid antigens presented by the major histocompatibility complex class I-related protein …
T-cell activation by lipopeptide antigens
I Van Rhijn, DM Zajonc, IA Wilson, DB Moody - Current opinion in …, 2005 - Elsevier
The discovery of the CD1 antigen-presenting system reveals that T cells survey the lipid
content of target cells via T-cell receptor (TCR) contact with CD1 bound to lipids, glycolipids …
content of target cells via T-cell receptor (TCR) contact with CD1 bound to lipids, glycolipids …
Invariant Vα14 chain NKT cells promote Plasmodium berghei circumsporozoite protein-specific gamma interferon-and tumor necrosis factor alpha-producing CD8+ T …
S Korten, RJ Anderson, CM Hannan… - Infection and …, 2005 - Am Soc Microbiol
Understanding the protective mechanism in the liver induced by recombinant vaccines
against the pre-erythrocytic stages of malaria is important for vaccine development. Most …
against the pre-erythrocytic stages of malaria is important for vaccine development. Most …