Lectins: tools for the molecular understanding of the glycocode
M Ambrosi, NR Cameron, BG Davis - Organic & biomolecular …, 2005 - pubs.rsc.org
Recent progress in glycobiology has revealed that cell surface oligosaccharides play an
essential role in recognition events. More precisely, these saccharides may be complexed …
essential role in recognition events. More precisely, these saccharides may be complexed …
Mannose‐binding lectin: biology and clinical implications
DL Worthley, PG Bardy… - Internal medicine journal, 2005 - Wiley Online Library
The innate host defence molecule mannose‐binding lectin (MBL) has attracted great interest
as a potential candidate for passive immunotherapy to prevent infection. MBL is a multimeric …
as a potential candidate for passive immunotherapy to prevent infection. MBL is a multimeric …
Functional analysis of the classical, alternative, and MBL pathways of the complement system: standardization and validation of a simple ELISA
MA Seelen, A Roos, J Wieslander, TE Mollnes… - Journal of …, 2005 - Elsevier
Primary defence against invading microorganisms depends on a functional innate immune
system and the complement system plays a major role in such immunity. Deficiencies in one …
system and the complement system plays a major role in such immunity. Deficiencies in one …
Modifier genetics: cystic fibrosis
GR Cutting - Annu. Rev. Genomics Hum. Genet., 2005 - annualreviews.org
▪ Abstract Cystic fibrosis (CF) is the most common lethal autosomal recessive disorder in the
Caucasian population, affecting about 30,000 individuals in the United States. The gene …
Caucasian population, affecting about 30,000 individuals in the United States. The gene …
The mannose‐binding lectin gene polymorphisms and systemic lupus erythematosus: two case–control studies and a meta‐analysis
Y Ho Lee, T Witte, T Momot, RE Schmidt… - Arthritis & …, 2005 - Wiley Online Library
Objective Mannose‐binding lectin (MBL) enhances opsonization and activates complement.
Dysfunctional alleles of MBL have been associated with low plasma concentrations of MBL …
Dysfunctional alleles of MBL have been associated with low plasma concentrations of MBL …
Association between mannose-binding lectin gene polymorphisms and susceptibility to severe acute respiratory syndrome coronavirus infection
H Zhang, G Zhou, L Zhi, H Yang, Y Zhai… - The Journal of …, 2005 - academic.oup.com
Background Genetic determinants of susceptibility to severe acute respiratory syndrome
coronavirus (SARS-CoV) infection remain unknown. We assessed whether mannose …
coronavirus (SARS-CoV) infection remain unknown. We assessed whether mannose …
Mannan-binding-lectin-associated serine proteases, characteristics and disease associations
R Sørensen, S Thiel, JC Jensenius - Springer seminars in …, 2005 - Springer
Abstract Mannan-binding lectin (MBL)-associated serine proteases (MASPs) circulate in
plasma as zymogens in complexes with MBL and with L-and H-ficolin. Upon binding of MBL …
plasma as zymogens in complexes with MBL and with L-and H-ficolin. Upon binding of MBL …
The two major oligomeric forms of human mannan-binding lectin: chemical characterization, carbohydrate-binding properties, and interaction with MBL-associated …
F Teillet, B Dublet, JP Andrieu, C Gaboriaud… - The Journal of …, 2005 - journals.aai.org
Mannan-binding lectin (MBL) is an oligomeric C-type lectin assembled from homotrimeric
structural units that binds to neutral carbohydrates on microbial surfaces. It forms individual …
structural units that binds to neutral carbohydrates on microbial surfaces. It forms individual …
Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk
S Saevarsdottir, OO Oskarsson, T Aspelund… - The Journal of …, 2005 - rupress.org
Inflammation can predispose to myocardial infarction (MI), and mannan binding lectin (MBL)
promotes phagocytic clearance of inflammatory agents, but the predictive value of MBL …
promotes phagocytic clearance of inflammatory agents, but the predictive value of MBL …
Protective molecules–C-reactive protein (CRP), serum amyloid P (SAP), pentraxin3 (PTX3), mannose-binding lectin (MBL), and apolipoprotein A1 (Apo A1), and their …
MS Kravitz, M Pitashny, Y Shoenfeld - Journal of clinical immunology, 2005 - Springer
Apoptotic defects and impaired clearance of cellular debris are considered key events in the
development of autoimmunity, as they can contribute to autoantigen overload, and may …
development of autoimmunity, as they can contribute to autoantigen overload, and may …