The RGS7 (R7) family of RGS proteins bound to the divergent Gβ subunit Gβ5 is a crucial
regulator of G protein–coupled receptor (GPCR) signaling in the visual and nervous …

Autonomic nervous system plays an important role in the regulation of mammalian heart,
and it is divided into the sympathetic and parasympathetic (vagal) subsystems. The …

The mammalian RFamide-related peptide RFRP1 was found to signal through the
neuropeptide FF 2 receptor expressed in Xenopus oocytes. The peptide induced a dose …

Certain transmitters inhibit Kir3 (GIRK) channels, resulting in neuronal excitation. We
analysed signalling mechanisms for substance P (SP)‐induced Kir3 inhibition in relation to …

The subfamily of G-protein-linked inwardly rectifying potassium channels (GIRKs) is coupled
to G-protein receptors throughout the CNS and in the heart. We used mutational analysis to …

Inward rectifier K+ channels (Kirs) act as a valve or a diode, allowing an inward current upon
hyperpolarization but not allowing exit of K+ ions upon depolarization. The degree of …

This study investigated cytoplasmic inter-subunit interactions between the Kir6. 2 and
SUR2A subunits of the cardiac ATP-sensitive potassium channel. The channels are a …

This invention provides isolated nucleic acids encoding mammalian NPFF receptors,
purified mammalian NPFF receptors, vectors comprising nucleic acid encoding mam malian …