Heterotrimeric G proteins are key players in transmembrane signaling by coupling a huge
variety of receptors to channel proteins, enzymes, and other effector molecules. Multiple …

▪ Abstract Adenosine and its receptors have been the topic of many recent reviews (–).
These reviews provide a good summary of much of the relevant literature—including the …

Caffeine is the most widely consumed psychostimulant substance, being self-administered
throughout a wide range of conditions and present in numerous dietary products. Due to its …

The olfactory system is able to detect a large number of chemical structures with a
remarkable sensitivity and specificity. Odorants are first detected by odorant receptors …

Background Mutants with targeted gene deletion ('knockout') or insertion (transgenic) of D 1,
D 2, D 3, D 4 and D 5 dopamine (DA) receptor subtypes are complemented by an increasing …

Alteration of dopamine neurotransmission during development can induce specific changes
in neuronal structure and function. Here, we report specific morphological and …

Genetic studies implicating the region of human chromosome 18p11. 2 in susceptibility to
bipolar disorder and schizophrenia have observed parent-of-origin effects that may be …

Neurochemical and pharmcological evidence obtained over the past 300 yr has indicated
that adenosine and dopamine interact functionally in the basal ganglia and that such …

Increasing evidence based on pharmacological and genetic studies suggests that retinoid
signaling plays an important role in developmental control of striatal neurons. In the present …

Spinophilin is a protein phosphatase‐1 (PP‐1)‐and actin‐binding protein that is enriched in
dendritic spines. Phosphorylation of the actin‐binding domain of rat spinophilin at one or …