Polymers such as Dacron® and polytetrafluoroethylene (PTFE) have been used in high flow
states with relative success but with limited application at lower flow states. Newer polymers …

The construction of tissue-engineered devices for medical applications is now possible in
vitro using cell culture and bioreactors. Although methods of incorporating them back into …

The ability of the biomimetic peptides YIGSR, PHSRN and RGD to selectively affect
adhesion and migration of human microvascular endothelial cells (MVEC) and vascular …

A number of vascular therapies could benefit from advanced methods for presentation of
angiogenic growth factors, including growth of endothelium on small caliber vascular grafts …

A tissue-engineered small-diameter arterial graft would be of benefit to patients requiring
vascular reconstructive procedures. Our objective was to produce a tissue-engineered …

In patients requiring coronary or peripheral vascular bypass procedures, autogenous arterial
or vein grafts remain as the conduit of choice even in the case of redo patients. It is in this …

Clinical in vitro endothelialization has been shown to increase the patency of synthetic
vascular grafts. The shear stress resistance of the cultured autologous endothelium …

BACKGROUND: Lack of endothelialization and abnormal smooth muscle cell (SMC) growth
adversely affect the outcome of vascular synthetic grafts. The aims of our study were to …

Biomedical implants often exhibit poor clinical performance due to the formation of a
periimplant avascular fibrous capsule. Surface modification of synthetic materials has been …

Implantation of biomaterials leads to the formation of an avascular, fibrotic capsule that
isolates the implant from the surrounding tissue. Previous studies have demonstrated that …