Directed evolution of enzyme stability

VGH Eijsink, S Gåseidnes, TV Borchert… - Biomolecular …, 2005 - Elsevier
Modern enzyme development relies to an increasing extent on strategies based on diversity
generation followed by screening for variants with optimised properties. In principle, these …

Applications of oxidoreductases: Recent progress

F Xu - Industrial Biotechnology, 2005 - liebertpub.com
Recent progress in the research and development of industrially and medically relevant
oxidoreductases is reviewed. Currently, the industrial-technical, food, and environmental …

High-throughput screens and selections of enzyme-encoding genes

A Aharoni, AD Griffiths, DS Tawfik - Current opinion in chemical biology, 2005 - Elsevier
The availability of vast gene repertoires from both natural sources (genomic and cDNA
libraries) and artificial sources (gene libraries) demands the development and application of …

Advances in biocatalytic synthesis of pharmaceutical intermediates

S Panke, M Wubbolts - Current opinion in chemical biology, 2005 - Elsevier
Biocatalytic synthesis of enantiomerically pure compounds for pharmaceutical intermediates
is gaining momentum. This is the result of advances in genomics, screening and evolution …

Combination of computational prescreening and experimental library construction can accelerate enzyme optimization by directed evolution

SA Funke, N Otte, T Eggert, M Bocola… - Protein Engineering …, 2005 - academic.oup.com
Chiral compounds can be produced efficiently by using biocatalysts. However, wild-type
enzymes often do not meet the requirements of a production process, making optimization …

An efficient chemoenzymatic synthesis of the bactericide lapyrium chloride

EM Rustoy, A Baldessari - 2005 - Wiley Online Library
An efficient route for large‐scale preparation of lapyrium chloride, a broad‐spectrum
antimicrobial surfactant, was developed from chloroacetic acid in four steps, three of them …

Industrial biotech at DSM: From concept to customer

C Laane, F Sijbesma - Value Creation: Strategies for the …, 2005 - Wiley Online Library
Industrial biotechnology is rapidly gaining momentum as a cost‐effective and
environmentally‐friendly technology for producing bio‐based chemicals, materials, and …

Enzyme engineering

BM McGrath - Directory of therapeutic enzymes, 2005 - taylorfrancis.com
Enzymes catalyze a myriad of chemical transformations, often with great specificity, exquisite
control, and remarkable rate enhancements, forming the basis for metabolism in all living …

Transformações químio-enzimáticas em esteróides

MMC Silva - 2005 - estudogeral.uc.pt
A utilização de enzimas como catalisadores selectivos e eficientes na transformação de
moléculas constitui uma tecnologia válida em síntese orgânica. As propriedades biológicas …

[PDF][PDF] Aril-és aralkil-metil ketonok sztereoszelektív redukciója élesztőkkel

E Balázs - core.ac.uk
A Talampanel az epilepszia kezelésére szolgáló, hatékony és mellékhatásoktól mentes
leendőbeli gyógyszerkészítmény, ami jelen pillanatban a második klinikai vizsgálatok …