Thymic cortical epithelium induces self tolerance

KP Goldman, CS Park, M Kim… - European journal of …, 2005 - Wiley Online Library
Because of its role in positive selection, the ability of cortical epithelium to induce tolerance
is controversial. On the one hand, experiments with transplanted thymuses showed that the …

Selection of CD4+CD25+ Regulatory T Cells by Self-Peptides

C Cozzo, MA Lerman, A Boesteanu, J Larkin… - … CD25+ Regulatory T …, 2005 - Springer
Regulatory T cells have been shown to prevent the development of autoimmune disease,
and can modulate immune responses during infections or following tissue transplantation …