Gap junctions are channel-forming structures in contacting plasma membranes that allow
direct metabolic and electrical communication between almost all cell types in the …

Gap junctions are clusters of intercellular channels that provide cells, in all metazoan
organisms, with a means of communicating directly with their neighbours. Surprisingly, two …

Abstract The Oct3/4 gene, a POU family transcription factor, has been noted as being
specifically expressed in embryonic stem cells and in tumor cells but not in cells of …

Regulation of gap junction (GJ) organization is critical for proper function of excitable tissues
such as heart and brain, yet mechanisms that govern the dynamic patterning of GJs remain …

Connexin gap junctions play an important role in hearing function, but the mechanism by
which this contribution occurs is unknown. Connexins in the cochlea are expressed only in …

Connexins have been known to be the protein building blocks of gap junctions and mediate
cell–cell communication. In contrast to the conventional dogma, recent evidence suggests …

Local injury induces a complex orchestrated response to stimulate healing of injured tissues,
cellular regeneration and phagocytosis. Practically, inflammation is defined as a defense …

In resistance arteries, spread of hyperpolarization from the endothelium to the adjacent
smooth muscle is suggested to be a crucial component of dilation resulting from …

The importance of connexins (Cxs) in cochlear functions has been demonstrated by the
finding that mutations in Cx genes cause a large proportion of sensorineural hearing loss …

Dysfunction of gap junctions (GJs) caused by mutations in connexin26 (Cx26) and Cx30
accounts for nearly half of all cases of hereditary nonsyndromic deafness cases. Although it …