Background. Infant and under-5 childhood mortality rates in developing countries have
declined significantly in the past 2 to 3 decades. However, 2 critical indicators, maternal and …

Birth defects (congenital anomalies) are the leading cause of death in babies under 1 year
of age. Neural tube defects (NTD), with a birth incidence of approximately 1/1000 in …

Before a 1996 US regulation requiring fortification of enriched cereal-grain products with
folic acid, 3 economic evaluations projected net economic benefits or cost savings of folic …

Biochemical and developmental pathways, mouse models, and positional evidence have
provided numerous candidate genes for the study of human neural tube defects. In a survey …

Since the publication of randomised trials showing firm evidence of prevention of neural
tube defects with periconceptional folic acid, there have been population health promotion …

Based on a 15-year old hypothesis, it is believed that an adequate ingestion of folate
vitamins decreases, whereas a nutritional depletion of folate increases the risk of colorectal …

Neural tube defects (NTDs) are the second most common birth defects (1 in 1000 live births)
in the world. Periconceptional maternal folate supplementation reduces NTD risk by 50 …

Major congenital anomalies occur in 2% to 3% of live births. Neural tube defects (NTDs),
cleft lip and palate, and cardiac anomalies are some of the most common. NTDs are a group …

Background: Public health officials recommend that women capable of becoming pregnant
use folic acid-containing supplements (FAS) to prevent neural tube defects (NTD) in their …

The following is a comprehensive review of the current understanding of the many important
roles of folic acid in the health of patients with epilepsy. A review of past and current …