Cardiovascular disease is a leading cause of mortality in the United States, and is a
significant cause of death worldwide. In 2002, it accounted for 38.0% of all deaths in the US …

▪ Abstract Cardiovascular disease (CVD) risk is the result of complex interactions between
genetic and environmental factors. During the past few decades, much attention has focused …

Background: Patients with familial hypercholesterolemia (FH) have a high risk of premature
cardiovascular disease (PCVD). Mutations in the LDL receptor (LDLR) gene and the …

We studied the association of six common polymorphisms of four genes related to lipid
metabolism with serum lipid levels. We selected single-nucleotide polymorphisms (SNPs) in …

Despite many advances in the management of cardiovascular risk factors, atherosclerotic
cardiovascular disease continues to be the dominant cause of death in the United States for …

Serum cholesterol is a major risk factor for cardiovascular disease. Total cholesterol, LDL
cholesterol and triglycerides are positively related to cardiovascular disease, while HDL …

The objective of this study was to evaluate the kinetics of both free and esterified forms of
cholesterol contained in a emulsion that binds to LDL receptors (LDE) in subjects with …

La hipercolesterolemia familiar es un trastorno hereditario autosómico dominante del
metabolismo de las lipoproteínas, que se caracteriza por unas concentraciones plasmáticas …

Familial lipoprotein disorders are seen frequently in subjects with premature coronary artery
disease. The genetic basis for several dyslipoproteinemias has been elucidated in the past …

For over three decades it has been recognized that a high level of total blood cholesterol,
particularly in the form of LDL cholesterol (LDL-C), is a major risk factor for developing …