Up to 50 or 60% of patients with chronic epilepsy have various mood disorders including
depression and anxiety. Whereas the relationship between epilepsy and depression has …

Advances made in diverse areas of neuroscience suggest that neurotransmitter systems,
additional to the monoaminergic, contribute to the pathophysiology of mood disorders. This …

No consensus has been reached with regard to the treatment of bouts of acute mania in
various parts of the world. Controlled clinical trials have, at last, provided irrefutable …

Objectives: To review evidence about mechanisms and consequences of relationships
between bipolar and substance use disorders. Methods: Articles were identified using a …

Patienten mit einer chronischen Epilepsie entwickeln in bis zu 50–60% psychiatrische
Komplikationen wie Depressionen, Angsterkrankungen und Psychosen. Während die …

In bipolar patients, maintenance treatment with anticonvulsive agents is a valid alternative to
lithium. These agents have widely varying mechanisms of action. Some of these …

Objetivos: Valorar la eficacia analgésica de la gabapentina (GBP) en pacientes con dolor
raquídeo crónico (DRC), que no han respondido adecuadamente a los tratamientos …

There is no established dosage or blood-level target, although levels can be used to monitor
adherence or assess drug metabolism. In clinical practice, the dosage is increased …