Prevention of type 1 diabetes mellitus requires early intervention in the autoimmune process
directed against β cells of the pancreatic islets of Langerhans. This autoimmune …

Bidens pilosa is claimed to be useful for immune or anti-inflammatory disorders; however,
little scientific evidence has been published concerning its function. In this paper, immune …

Since their discovery decades ago, regulatory T (Treg) cells have prompted many
investigations into their potential role in the generation or prevention of autoimmune …

Localized gene transfer has the potential to introduce immunosuppressive molecules only
into the transplanted allograft, which would limit systemic side effects, and prolong allograft …

The most intensively studied autoimmune disorder, type 1 diabetes mellitus (DM1), has
attracted perhaps the greatest interest for gene-based therapeutic and prophylactic …

Type 1 diabetes mellitus is an autoimmune disease caused by a culmination of noxious
processes of autoimmunity composed of various components of the innate and adaptive …

Polymeric gene delivery systems have been developed to overcome problems caused by
viral carriers. They are low cytotoxic, have no size limit, are convenient in handling, of low …

One of the most exciting advances in the field of gene therapy in recent years is the
establishment of the antigen-specific T cell as a vector for the delivery of genetically-derived …

ACADEMISCHH PROEFSCHRIFT terr verkrijging van de graad van doctor aann de
Universiteit van Amsterdam opp gezag vann de Rector Magnificus prof. mr.. PF van der …

Conclusions The gene therapy of autoimmunity has held many promises for the last ten
years, owing to its potential as an alternative therapeutic approach for diseases lacking a …