The AMP-activated protein kinase (AMPK) is an evolutionarily conserved sensor of cellular
energy status, and recent data demonstrate that it also plays a critical role in systemic …

Epidemiological studies suggest that physically active individuals have a 30–50% lower risk
of developing type 2 diabetes than do sedentary persons and that physical activity confers a …

OBJECTIVE—This meta-analysis was undertaken to obtain insight regarding the shape and
strength of the relationship between alcohol consumption and the risk of type 2 diabetes, the …

The pathological sequence for type 2 diabetes is complex and entails many different
elements that act in concert to cause that disease. This review proposes a sequence of …

Currently, modern chronic diseases, including cardiovascular diseases, Type 2 diabetes,
metabolic syndrome, and cancer, are the leading killers in Westernized society and are …

Prevention of type 2 diabetes by intensive lifestyle intervention designed to achieve and
maintain ideal body weight was assessed in subjects with impaired glucose tolerance (IGT) …

ContextLactation is associated with improved glucose and insulin homeostasis,
independent of weight change. ObjectiveTo evaluate the association between lactation …

OBJECTIVE: We wanted to assess the effect of rapid diet-induced weight loss on the
function of obese, knee osteoarthritis (OA) patients. METHODS: Eighty patients with knee …

▪ Abstract Although it is widely believed that type 2 diabetes mellitus is the result of a
complex interplay between genetic and environmental factors, compelling evidence from …

To examine the molecular mechanisms by which plasma amino acid elevation impairs
insulin action, we studied seven healthy men twice in random order during infusion of an …