Development and pharmacological characterization of a rat model of osteoarthritis pain

JD Pomonis, JM Boulet, SL Gottshall, S Phillips… - Pain, 2005 - Elsevier
Osteoarthritis (OA) is an age-related joint disease characterized by degeneration of articular
cartilage and is associated with chronic pain. Although several experimental models of OA …

Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis

J Fernihough, C Gentry, S Bevan, J Winter - Neuroscience letters, 2005 - Elsevier
Pain in osteoarthritis (OA) remains an intractable problem in a majority of patients, with many
of the commonly prescribed analgesics providing insufficient relief and considerable side …