FGF‐2 enhances the mitotic and chondrogenic potentials of human adult bone marrow‐derived mesenchymal stem cells
LA Solchaga, K Penick, JD Porter… - Journal of cellular …, 2005 - Wiley Online Library
Human mesenchymal stem cells (hMSCs) expanded with and without fibroblast growth
factor (FGF) supplementation were compared with respect to their proliferation rate, ability to …
factor (FGF) supplementation were compared with respect to their proliferation rate, ability to …
Characterizing the viscoelastic properties of thin hydrogel-based constructs for tissue engineering applications
We present a novel indentation method for characterizing the viscoelastic properties of
alginate and agarose hydrogel based constructs, which are often used as a model system of …
alginate and agarose hydrogel based constructs, which are often used as a model system of …
Immunophenotypic analysis of human articular chondrocytes: changes in surface markers associated with cell expansion in monolayer culture
J Diaz‐Romero, JP Gaillard, SP Grogan… - Journal of cellular …, 2005 - Wiley Online Library
Cartilage tissue engineering relies on in vitro expansion of primary chondrocytes. Monolayer
is the chosen culture model for chondrocyte expansion because in this system the …
is the chosen culture model for chondrocyte expansion because in this system the …
[HTML][HTML] Wnt-3a regulates chondrocyte differentiation via c-Jun/AP-1 pathway
SG Hwang, SS Yu, SW Lee, JS Chun - FEBS letters, 2005 - Elsevier
Our previous study indicated that interleukin (IL)-1β induces expression of several Wnt
proteins in chondrocytes and causes chondrocyte dedifferentiation via the c-Jun/activator …
proteins in chondrocytes and causes chondrocyte dedifferentiation via the c-Jun/activator …
Regulation of β-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of α-catenin
SG Hwang, SS Yu, JH Ryu, HB Jeon, YJ Yoo… - Journal of Biological …, 2005 - ASBMB
Accumulation of β-catenin and subsequent stimulation of β-catenin-T cell-factor
(Tcf)/lymphoid-enhancerfactor (Lef) transcriptional activity causes dedifferentiation of …
(Tcf)/lymphoid-enhancerfactor (Lef) transcriptional activity causes dedifferentiation of …
[HTML][HTML] Immature murine articular chondrocytes in primary culture: a new tool for investigating cartilage
C Salvat, A Pigenet, L Humbert, F Berenbaum… - Osteoarthritis and …, 2005 - Elsevier
OBJECTIVE: Many genetically modified animal models are providing new keys for unlocking
the pathophysiology of cartilage degradation. To produce a tool for cellular and molecular …
the pathophysiology of cartilage degradation. To produce a tool for cellular and molecular …
[HTML][HTML] Human articular chondrocytes exhibit sexual dimorphism in their responses to 17β-estradiol
RC Kinney, Z Schwartz, K Week, MK Lotz… - Osteoarthritis and …, 2005 - Elsevier
OBJECTIVE: The higher incidence of osteoarthritis in females suggests that there may be
intrinsic sex-specific differences in human articular chondrocytes. 17β-Estradiol (E2) …
intrinsic sex-specific differences in human articular chondrocytes. 17β-Estradiol (E2) …
Subculture of chondrocytes on a collagen type I-coated substrate with suppressed cellular dedifferentiation
M Kino-Oka, S Yashiki, Y Ota, Y Mushiaki… - Tissue …, 2005 - liebertpub.com
To evaluate the degree of cellular dedifferentiation, subculture of chondrocytes was
conducted on a surface coated with collagen type I at a density of 1.05 mg/cm2. In the …
conducted on a surface coated with collagen type I at a density of 1.05 mg/cm2. In the …
c-Jun/activator protein-1 mediates interleukin-1β-induced dedifferentiation but not cyclooxygenase-2 expression in articular chondrocytes
SG Hwang, SS Yu, H Poo, JS Chun - Journal of Biological Chemistry, 2005 - ASBMB
Interleukin (IL)-1β is a major catabolic pro-inflammatory cytokine involved in cartilage
destruction-associated processes, such as loss of the differentiated chondrocyte phenotype …
destruction-associated processes, such as loss of the differentiated chondrocyte phenotype …
Stepwise mechanical stretching inhibits chondrogenesis through cell–matrix adhesion mediated by integrins in embryonic rat limb-bud mesenchymal cells
K Onodera, I Takahashi, Y Sasano, JW Bae… - European journal of cell …, 2005 - Elsevier
Biomechanical forces are major epigenetic factors that determine the form and differentiation
of skeletal tissues, and may be transduced through cell adhesion to the intracellular …
of skeletal tissues, and may be transduced through cell adhesion to the intracellular …