Cell Wall Integrity Signaling in Saccharomyces cerevisiae

DE Levin - Microbiology and molecular biology reviews, 2005 - Am Soc Microbiol
The yeast cell wall is a highly dynamic structure that is responsible for protecting the cell
from rapid changes in external osmotic potential. The wall is also critical for cell expansion …

[HTML][HTML] Molecular organization of target of rapamycin complex 2

S Wullschleger, R Loewith, W Oppliger… - Journal of Biological …, 2005 - ASBMB
The target of rapamycin (TOR), a highly conserved serine/threonine kinase, plays a central
role in the control of eukaryotic cell growth. TOR exists in two functionally and structurally …

Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization

Y Kamada, Y Fujioka, NN Suzuki… - … and cellular biology, 2005 - Am Soc Microbiol
The target of rapamycin (TOR) protein kinases, Tor1 and Tor2, form two distinct complexes
(TOR complex 1 and 2) in the yeast Saccharomyces cerevisiae. TOR complex 2 (TORC2) …

Mutations in the Arabidopsis Phosphoinositide Phosphatase Gene SAC9 Lead to Overaccumulation of PtdIns(4,5)P2 and Constitutive Expression of the Stress …

ME Williams, J Torabinejad, E Cohick, K Parker… - Plant …, 2005 - academic.oup.com
Phosphoinositides (PIs) are signaling molecules that regulate cellular events including
vesicle targeting and interactions between membrane and cytoskeleton …

The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4, 5-bisphosphate …

M Fadri, A Daquinag, S Wang, T Xue… - Molecular biology of the …, 2005 - Am Soc Cell Biol
Phosphatidylinositol-4, 5-bisphosphate [PtdIns (4, 5) P2] is a key second messenger that
regulates actin and membrane dynamics, as well as other cellular processes. Many of the …

Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast

I Rodríguez-Escudero, FM Roelants… - Biochemical …, 2005 - portlandpress.com
The mammalian signalling pathway involving class I PI3K (phosphoinositide 3-kinase),
PTEN (phosphatidylinositol 3-phosphatase) and PKB (protein kinase B)/c-Akt has roles in …

The phosphoinositide phosphatase Sjl2 is recruited to cortical actin patches in the control of vesicle formation and fission during endocytosis

CJ Stefan, SM Padilla, A Audhya… - Molecular and cellular …, 2005 - Am Soc Microbiol
The Saccharomyces cerevisiae synaptojanin-like proteins (Sjl1, Sjl2, and Sjl3) are
phosphoinositide (PI) phosphatases that regulate PI metabolism in the control of actin …

Saccharomyces cerevisiaeTSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex

HL Ho, YS Shiau, MY Chen - Current genetics, 2005 - Springer
Saccharomyces cerevisiae TSC11/AVO3 is an essential gene encoding one component of
TORC2, a multi-protein complex of yeast Tor2p that also contains Lst8p, Avo1p, and Avo2p …

[HTML][HTML] Phosphatidylinositol-4-phosphate 5-kinase regulates fission yeast cell integrity through a phospholipase C-mediated protein kinase C-independent pathway

L Deng, R Sugiura, K Ohta, K Tada, M Suzuki… - Journal of Biological …, 2005 - ASBMB
Fission yeast its3-1 mutant is an allele of the essential gene its3+ that encodes a
phosphatidylinositol-4-phosphate 5-kinase (PIP5K) that produces phosphatidylinositol 4, 5 …

Probing the complex system of metabolic integration

DM Downs, GE Schmitz, E Skovran - Progress in Nucleic Acid Research …, 2005 - Elsevier
Publisher Summary This chapter focuses on probing the complex system of metabolic
integration. A central premise of this work is that metabolic integration can be perceived as a …