Adenosine and brain function
BB Fredholm, JF Chen, RA Cunha… - Int Rev …, 2005 - books.google.com
A. Cellular and Subcellular Localization B. Pharmacological Tools to Study Adenosine
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …
Neuroprotection by adenosine in the brain: From A1 receptor activation to A2A receptor blockade
RA Cunha - Purinergic signalling, 2005 - Springer
Adenosine is a neuromodulator that operates via the most abundant inhibitory adenosine A
1 receptors (A 1 Rs) and the less abundant, but widespread, facilitatory A 2A Rs. It is …
1 receptors (A 1 Rs) and the less abundant, but widespread, facilitatory A 2A Rs. It is …
Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function
The existence of A 2A-D 2 heteromeric complexes is based on coimmunoprecipitation
studies and on fluorescence resonance energy transfer and bioluminescence resonance …
studies and on fluorescence resonance energy transfer and bioluminescence resonance …
Therapeutic potential of adenosine A2A receptor antagonists in Parkinson's disease
K Xu, E Bastia, M Schwarzschild - Pharmacology & therapeutics, 2005 - Elsevier
In the pursuit of improved treatments for Parkinson's disease (PD), the adenosine A2A
receptor has emerged as an attractive nondopaminergic target. Based on the compelling …
receptor has emerged as an attractive nondopaminergic target. Based on the compelling …
Different synaptic and subsynaptic localization of adenosine A2A receptors in the hippocampus and striatum of the rat
Adenosine A2A receptors are most abundant in the striatum where they control the
striatopallidal pathway thus controlling locomotion. Extra-striatal A2A receptors are …
striatopallidal pathway thus controlling locomotion. Extra-striatal A2A receptors are …
Co‐localization and functional interaction between adenosine A2A and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum
The anti‐Parkinsonian effect of glutamate metabotropic group 5 (mGluR5) and adenosine
A2A receptor antagonists is believed to result from their ability to postsynaptically control the …
A2A receptor antagonists is believed to result from their ability to postsynaptically control the …
Animal models for the study of adenosine receptor function
R Yaar, MR Jones, JF Chen… - Journal of cellular …, 2005 - Wiley Online Library
Adenosine receptors represent a family of G‐protein coupled receptors that are ubiquitously
expressed in a wide variety of tissues. This family contains four receptor subtypes: A1 and …
expressed in a wide variety of tissues. This family contains four receptor subtypes: A1 and …
New therapies for the treatment of Parkinson's disease: adenosine A2A receptor antagonists
A Pinna, J Wardas, N Simola, M Morelli - Life sciences, 2005 - Elsevier
The development of non-dopaminergic therapies for the treatment of Parkinson's disease
(PD) has attracted much interest in recent years. Among new different classes of drugs …
(PD) has attracted much interest in recent years. Among new different classes of drugs …
Coexpression of vesicular glutamate transporter‐3 and γ‐aminobutyric acidergic markers in rat rostral medullary raphe and intermediolateral cell column
RL Stornetta, DL Rosin, JR Simmons… - Journal of …, 2005 - Wiley Online Library
Markers of serotonergic, γ‐aminobutyric acid (GABA)‐ergic (glutamic acid decarboxylase,
67 kDa isoform; GAD‐67), and glutamatergic transmission (vesicular glutamate transporter …
67 kDa isoform; GAD‐67), and glutamatergic transmission (vesicular glutamate transporter …
The protective effect of adenosine A2A receptor antagonism in cerebral ischemia
F Pedata, M Gianfriddo, D Turchi, A Melani - Neurological research, 2005 - Taylor & Francis
Objectives: We reviewed our most recent work on the protective effect of adenosine
A2Aantagonism in cerebral ischemia. Methods: Focal ischemia was produced in rats by …
A2Aantagonism in cerebral ischemia. Methods: Focal ischemia was produced in rats by …