[HTML][HTML] A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake

LR Devireddy, C Gazin, X Zhu, MR Green - Cell, 2005 - cell.com
The lipocalin mouse 24p3 has been implicated in diverse physiological processes, including
apoptosis due to interleukin-3 (IL-3) deprivation and iron transport. Here we report cloning of …

Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim

Y Zhao, J Tan, L Zhuang, X Jiang… - Proceedings of the …, 2005 - National Acad Sciences
Inhibitors of histone deacetylases (HDACIs) are a new generation of anticancer agents that
selectively kill tumor cells. However, the molecular basis for their tumor selectivity is not well …

Drug resistance in cancer

E Yagüe, S Raguz - British Journal of Cancer, 2005 - nature.com
Cancer Research UK has recently sponsored a meeting, organized by the UK Medical
Research Council, on cancer drug resistance. Several of the molecular mechanisms …

[PDF][PDF] P210 BCR-ABL tyrosine kinase prevents apoptotic cell death through multiple pathways converging at mitochondrial membranes

M Mancini, N Calonghi, E Pagnotta, L Masotti… - Gene Ther Mol Biol, 2005 - Citeseer
Extended survival of clonal hematopoietic progenitors associated with the bcr-abl
expression has a key role in the pathogenesis of Chronic Myeloid Leukemia (CML) and may …