During the past two decades, an important focus of pain research has been the study of
chronic pain mechanisms, particularly the processes that lead to the abnormal sensitivity …

This review examines recently recognized roles of immunological processes in pain
modulation and explores the potential implications of these immunologically derived …

Activation of p38 mitogen‐activated protein kinase (p38) in spinal microglia is implicated in
spinal nociceptive processing. Minocycline, a tetracycline derivative, displays selective …

Proinflammatory cytokines, such as interleukin‐1β and tumour necrosis factor‐α, are
released by activated glial cells in the spinal cord and play a major role in pain facilitation …

This paper focuses on recent evidence of etiopathogenetic links between fibromyalgia and
life stress. From an etiologic point of view, studies concerning the role of adverse life events …

The mechanical impact of a spinal cord injury (SCI) triggers a cascade of secondary damage
that progressively destroys an increasing amount of tissue adjacent to the primary lesion …

Minocycline is a semi-synthetic second-generation tetracycline that penetrates well into the
central nervous system (CNS) via blood–brain barrier (Aronson, 1980). In addition to its …