Organic azides: an exploding diversity of a unique class of compounds

S Bräse, C Gil, K Knepper… - Angewandte Chemie …, 2005 - Wiley Online Library
Since the discovery of organic azides by Peter Grieß more than 140 years ago, numerous
syntheses of these energy‐rich molecules have been developed. In more recent times in …

Organische Azide–explodierende Vielfalt bei einer einzigartigen Substanzklasse

S Bräse, C Gil, K Knepper… - Angewandte Chemie, 2005 - Wiley Online Library
Seit der Entdeckung der organischen Azide vor über einhundertvierzig Jahren durch Peter
Grieß wurde eine Reihe von Synthesen für diese energiereichen Moleküle entwickelt. In …

Evanescent-field fluorescence-assisted lectin microarray: a new strategy for glycan profiling

A Kuno, N Uchiyama, S Koseki-Kuno, Y Ebe… - Nature …, 2005 - nature.com
Glycans have important roles in living organisms with their structural diversity. Thus,
glycomics, especially aspects involving the assignment of functional glycans in a high …

A Multifunctional Pasteurella multocida Sialyltransferase:  A Powerful Tool for the Synthesis of Sialoside Libraries

H Yu, H Chokhawala, R Karpel, H Yu… - Journal of the …, 2005 - ACS Publications
A multifunctional sialyltransferase has been cloned from Pasteurella multocida strain P-1059
and expressed in E. coli as a truncated C-terminal His6-tagged recombinant protein …

Structurally diverse dendritic libraries: A highly efficient functionalization approach using click chemistry

M Malkoch, K Schleicher, E Drockenmuller… - …, 2005 - ACS Publications
The high fidelity and efficiency of Click chemistry are exploited in the synthesis of a library of
chain end functionalized dendritic macromolecules. In this example, the selectivity of the Cu …

Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12

DA Calarese, HK Lee, CY Huang… - Proceedings of the …, 2005 - National Acad Sciences
Human antibody 2G12 neutralizes a broad range of HIV-1 isolates. Hence, molecular
characterization of its epitope, which corresponds to a conserved cluster of oligomannoses …

Efficient synthesis of water-soluble calixarenes using click chemistry

EH Ryu, Y Zhao - Organic letters, 2005 - ACS Publications
Several water-soluble calix [4] arenes were synthesized via Huisgen 1, 3-dipolar
cycloaddition between azides and alkynes. Cationic, anionic, and nonionic calixarenes were …

Protein glycosylation: new challenges and opportunities

CH Wong - The Journal of organic chemistry, 2005 - ACS Publications
Protein glycosylation is the most complex post-translational modification process. More than
50% of proteins in humans are glycosylated, while bacteria such as E. coli does not have …

Fluorous-based carbohydrate microarrays

KS Ko, FA Jaipuri, NL Pohl - Journal of the American Chemical …, 2005 - ACS Publications
The success of microarrays, such as DNA chips, for biosample screening with minimal
sample usage has led to a variety of technologies for assays on glass slides. Unfortunately …

1, 2, 3-Triazole and its derivatives. Development of methods for the formation of the triazole ring

VP Krivopalov, OP Shkurko - Russian chemical reviews, 2005 - iopscience.iop.org
Data on the synthetic routes to substituted 1, 2, 3-triazoles, including those containing
functional groups, based on cyclisation of various nitrogen compounds published during the …