Role of the Ras-association domain family 1 tumor suppressor gene in human cancers
A Agathanggelou, WN Cooper, F Latif - Cancer research, 2005 - AACR
In recent years, the list of tumor suppressor genes (or candidate TSG) that are inactivated
frequently by epigenetic events rather than classic mutation/deletion events has been …
frequently by epigenetic events rather than classic mutation/deletion events has been …
The tumor suppressor RASSF1A in human carcinogenesis: an update
R Dammann, U Schagdarsurengin, C Seidel… - Histology and …, 2005 - digitum.um.es
Loss of heterozygosity of the small arm of chromosome 3 is one of the most common
alterations in human cancer. Most notably, a segment in 3p21. 3 is frequently lost in lung …
alterations in human cancer. Most notably, a segment in 3p21. 3 is frequently lost in lung …
World Health Organization classification of tumours: Pathology & genetics of tumours of the urinary system and male genital organs
TY Chan - Urology, 2005 - goldjournal.net
This 2004 volume in the World Health Organization series on histologic and genetic typing
of human tumors covers tumors of the kidney, urinary system, prostate, testis and …
of human tumors covers tumors of the kidney, urinary system, prostate, testis and …
Tumor Susceptibility of Rassf1a Knockout Mice
The human Ras association domain family 1 (RASSF1) gene is located at 3p21. 3 in an area
that is believed to harbor at least one important tumor suppressor gene. The two major …
that is believed to harbor at least one important tumor suppressor gene. The two major …
Promoter hypermethylation in benign breast epithelium in relation to predicted breast cancer risk
CM Lewis, LR Cler, DW Bu… - Clinical Cancer …, 2005 - AACR
Introduction: The tumor suppressor genes RASSF1A, APC, H-cadherin, RARβ2, and cyclin
D2 are methylated more frequently in breast cancer than in adjacent benign tissue …
D2 are methylated more frequently in breast cancer than in adjacent benign tissue …
Methylation of the Tumor Suppressor Gene RASSF1A in Human Tumors
GP Pfeifer, R Dammann - Biochemistry (Moscow), 2005 - Springer
Loss of heterozygosity of a segment at 3p21. 3 is frequently observed in lung cancer and
several other carcinomas. We have identified the Ras-association domain family 1A gene …
several other carcinomas. We have identified the Ras-association domain family 1A gene …
Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter
M Strunnikova, U Schagdarsurengin… - … and cellular biology, 2005 - Am Soc Microbiol
Epigenetic inactivation of the RASSF1A tumor suppressor by CpG island methylation was
frequently detected in cancer. However, the mechanisms of this aberrant DNA methylation …
frequently detected in cancer. However, the mechanisms of this aberrant DNA methylation …
Enhancement of In vitro and In vivo Tumor Cell Radiosensitivity by the DNA Methylation Inhibitor Zebularine
H Dote, D Cerna, WE Burgan, DJ Carter, MA Cerra… - Clinical cancer …, 2005 - AACR
Aberrant DNA hypermethylation is a frequent finding in tumor cells, which has suggested
that inhibition of DNA methylation may be an effective cancer treatment strategy. Because …
that inhibition of DNA methylation may be an effective cancer treatment strategy. Because …
Epigenetic silencing of DSC3 is a common event in human breast cancer
MM Oshiro, CJ Kim, RJ Wozniak, DJ Junk… - Breast Cancer …, 2005 - Springer
Abstract Introduction Desmocollin 3 (DSC3) is a member of the cadherin superfamily of
calcium-dependent cell adhesion molecules and a principle component of desmosomes …
calcium-dependent cell adhesion molecules and a principle component of desmosomes …
[HTML][HTML] RASSF1A and NORE1A methylation and BRAFV600E mutations in thyroid tumors
N Nakamura, JA Carney, L Jin, S Kajita, J Pallares… - Laboratory …, 2005 - Elsevier
We analyzed RASSF1A and NORE1A methylation and BRAF mutation in 89 thyroid tumors,
42 non-neoplastic thyroid tissues and three thyroid tumor cell lines using polymerase chain …
42 non-neoplastic thyroid tissues and three thyroid tumor cell lines using polymerase chain …