Severe sepsis leading to shock is the principal cause of death in intensive care units. It is a
systemic inflammatory response caused by excessive secretion of pro-inflammatory …

High mobility group box 1 (HMGB1) is a novel late mediator of inflammatory responses that
contributes to endotoxin-induced acute lung injury and sepsis-associated lethality. Although …

Relaxation techniques are part of the integrative medicine movement that is of growing
importance for mainstream medicine. Complementary medical therapies have the potential …

Leukocyte activation and production of inflammatory mediators and reactive oxygen species
are important in the pathogenesis of lipopolysaccharide (LPS)-induced acute lung injury …

Coal dust inhalation induces oxidative damage and inflammatory infiltration on lung
parenchyma. Thus, the aim of this study was to determine whether N-acetylcysteine (NAC) …

Background: Chronic obstructive pulmonary disease (COPD) is accompanied by both
airway and systemic inflammation and by oxidative stress. This study aimed to characterise …

BACKGROUND: The gut is a target organ of shock/resuscitation (S/R); however, it also
contributes to distant inflammation through the generation of oxidants. S/R with antioxidants …

purpose. To determine the effect of pyrrolidine dithiocarbamate (PDTC), a nuclear factor
(NF)-κB inhibitor, on chemokine and chemokine receptor expression and thus elucidate the …

Multiple intracellular signaling pathways involving kinases, transcriptional factors, and the
expression of immunoregulatory mediators are altered in sepsis. Recent data have shown …

Pro-inflammatory cytokines initiate the vascular inflammatory response via upregulation of
adhesion molecules on the endothelium. Recent observations suggest that reactive oxygen …