Respiratory rehabilitation after acute exacerbation of COPD may reduce risk for readmission and mortality–a systematic review

MA Puhan, M Scharplatz, T Troosters, J Steurer - Respiratory research, 2005 - Springer
Background Acute exacerbations of chronic obstructive pulmonary disease (COPD)
represent a major burden for patients and health care systems. Respiratory rehabilitation …

How should COPD patients exercise during respiratory rehabilitation? Comparison of exercise modalities and intensities to treat skeletal muscle dysfunction

MA Puhan, HJ Schünemann, M Frey, M Scharplatz… - Thorax, 2005 - thorax.bmj.com
Background: Physical exercise is an important component of respiratory rehabilitation
because it reverses skeletal muscle dysfunction, a clinically important manifestation of …

Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease

JJ Soler-Cataluña, MÁ Martínez-García, PR Sánchez… - Thorax, 2005 - thorax.bmj.com
Background: Patients with chronic obstructive pulmonary disease (COPD) often present with
severe acute exacerbations requiring hospital treatment. However, little is known about the …

Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised …

M Decramer, M Rutten-van Mölken, PNR Dekhuijzen… - The Lancet, 2005 - thelancet.com
Background Increased oxidative stress is important in the pathogenesis of chronic
obstructive pulmonary disease (COPD). We postulated that treatment with the antioxidant N …

Risk factors for rehospitalisation in COPD: role of health status, anxiety and depression

G Gudmundsson, T Gislason, C Janson… - European respiratory …, 2005 - Eur Respiratory Soc
The aim of the present study was to analyse the risk of rehospitalisation in patients with
chronic obstructive pulmonary disease and associated risk factors. This prospective study …

Factors associated with medication nonadherence in patients with COPD

J George, DCM Kong, R Thoman, K Stewart - Chest, 2005 - Elsevier
Study objectives: To identify the predictors of medication adherence in patients with COPD
and contrast the health beliefs, experiences, and behaviors of COPD patients self-reporting …

Physiological changes during symptom recovery from moderate exacerbations of COPD

CM Parker, N Voduc, SD Aaron… - European …, 2005 - Eur Respiratory Soc
Acute exacerbations of chronic obstructive disease (AECOPD) are characterised by
worsening dyspnoea that is variably prolonged. In this study, physiological changes during …

Prevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator: a randomized trial

DE Niewoehner, K Rice, C Cote, D Paulson… - Annals of internal …, 2005 - acpjournals.org
Background: Patients with chronic obstructive pulmonary disease (COPD) frequently
develop exacerbations, leading to major clinical and health resource use ramifications …

Exacerbations and time spent outdoors in chronic obstructive pulmonary disease

GC Donaldson, TMA Wilkinson, JR Hurst… - American journal of …, 2005 - atsjournals.org
Patients with chronic obstructive pulmonary disease have a progressive reduction in activity,
although its time scale and the contribution of exacerbations are unknown. A rolling cohort of …

MMP-9, TIMP-1 and inflammatory cells in sputum from COPD patients during exacerbation

PF Mercer, JK Shute, A Bhowmik, GC Donaldson… - Respiratory …, 2005 - Springer
Background Irreversible airflow obstruction in Chronic Obstructive Pulmonary Disease
(COPD) is thought to result from airway remodelling associated with aberrant inflammation …