JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome–negative CML, and megakaryocytic leukemia
J Jelinek, Y Oki, V Gharibyan, C Bueso-Ramos… - blood, 2005 - ashpublications.org
An activating 1849G> T mutation of JAK2 (Janus kinase 2) tyrosine kinase was recently
described in chronic myeloproliferative disorders (MPDs). Its role in other hematologic …
described in chronic myeloproliferative disorders (MPDs). Its role in other hematologic …
Leukemic transformation of polycythemia vera: a single center study of 23 patients
BACKGROUND Acute leukemia (AL) may occur as rare and late event of polycythemia vera
(PV). METHODS The current study included 23 patients who developed acute leukemia in a …
(PV). METHODS The current study included 23 patients who developed acute leukemia in a …
Abnormalities of GATA-1 in megakaryocytes from patients with idiopathic myelofibrosis
AM Vannucchi, A Pancrazzi, P Guglielmelli… - The American journal of …, 2005 - Elsevier
The abnormal megakaryocytopoiesis associated with idiopathic myelofibrosis (IM) plays a
role in its pathogenesis. Because mice with defective expression of transcription factor GATA …
role in its pathogenesis. Because mice with defective expression of transcription factor GATA …
Chromosome 7 deletions are associated with unfavorable prognosis in myelofibrosis with myeloid metaplasia
K Strasser-Weippl, M Steurer, M Kees, F Augustin… - Blood, 2005 - ashpublications.org
Several studies suggest a poor prognosis for patients with myelofibrosis (MF) with an
abnormal karyotype, but the prognostic impact of specific cytogenetic lesions is difficult to …
abnormal karyotype, but the prognostic impact of specific cytogenetic lesions is difficult to …
[PDF][PDF] JAK2 mutation 1849G> T is rare in acute leukemias but can be found in
MB Verstovsek, E Estey, HM Kantarjian, JPJ Issa - academia.edu
An activating 1849G> T mutation of JAK2 tyrosine kinase was recently described in chronic
myeloproliferative disorders (MPD). Its role in other hematological neoplasms is unclear. We …
myeloproliferative disorders (MPD). Its role in other hematological neoplasms is unclear. We …