During the past decade, our understanding of the pathophysiology of coronary artery
disease (CAD) has undergone a remarkable evolution. We review here how these advances …

Abstract The American Diabetes Association standards of medical care in diabetes are
presented. They are intended to provide clinicians, patients, researchers, payors, and other …

Context Little is known about lifetime prevalence or age of onset ofDSM-IVdisorders.
Objective To estimate lifetime prevalence and age-of-onset distributions ofDSM-IVdisorders …

Background Results of previous randomised trials have shown that interventions that lower
LDL cholesterol concentrations can significantly reduce the incidence of coronary heart …

Background Previous trials have demonstrated that lowering low-density lipoprotein (LDL)
cholesterol levels below currently recommended levels is beneficial in patients with acute …

Background Statins lower the levels of low-density lipoprotein (LDL) cholesterol and C-
reactive protein (CRP). Whether this latter property affects clinical outcomes is unknown …

ContextEvidence suggests that more intensive lowering of low-density lipoprotein
cholesterol (LDL-C) than is commonly applied clinically will provide further benefit in stable …

Background Recent trials have demonstrated better outcomes with intensive than with
moderate statin treatment. Intensive treatment produced greater reductions in both low …

BACKGROUND: Results of previous randomised trials have shown that interventions that
lower LDL cholesterol concentrations can significantly reduce the incidence of coronary …

Background—Previous studies suggest that erythrocyte membranes from intraplaque
hemorrhage into the necrotic core are a source of free cholesterol and may become a …