During the development of the mammalian central nervous system, neural stem cells and
their derivative progenitor cells generate neurons by asymmetric and symmetric divisions …

Prominin-1, originally found on neuroepithelial stem cells in mice, is a five transmembrane
domain cell-surface glycoprotein that localizes to membrane protrusions. Its homologue …

Apical plasma membrane constituents of mammalian neural stem/progenitor cells have
recently been implicated in maintaining their stem/progenitor cell state. Here, we report that …

The cerebellum is critical for motor coordination and cognitive function and is the target of
transformation in medulloblastoma, the most common malignant brain tumor in children …

The first non-hematopoietic mesenchymal stem cells (MSCs) were discovered by
Friedenstein in 1976, who described clonal, plastic adherent cells from bone marrow …

Abstract Human prominin-1/CD133 has been reported to be expressed in neural and
hematopoietic stem/progenitor cells and in embryonic, but not adult, epithelia. This lack of …

Medulloblastoma is the most common malignant brain tumor in children. It is thought to
result from the transformation of granule cell precursors (GCPs) in the developing …

Global gene expression profiling was performed on murine embryonic stem cells (ESCs)
induced to differentiate by removal of leukemia inhibitory factor (LIF) to identify genes whose …

Abstract Prominin‐1/CD133 is a plasma membrane marker found in several types of somatic
stem cells, including hematopoietic and neural stem cells. To study its role during …

Previous studies have shown that a targeted deletion of Ovol1 (previously known as movo1),
encoding a member of the Ovo family of zinc-finger transcription factors, leads to germ cell …