Few terms in the biomedical lexicon are as widely recognized as the phrase blood–brain
barrier (BBB). Indeed, it immediately conjures up a “barricade” between the blood and the …

Background Interest in airways inflammatory disease has increasingly focused on innate
immunity. We investigated several components of innate immunity in induced sputum of …

The endothelium of the adult vasculature is normally quiescent, with the exception of the
vasculature of the female reproductive system. However, in response to appropriate stimuli …

Brain hemorrhage is a severe complication of both neoplastic and nonneoplastic brain
disease. Mice deficient in the αvβ8 integrin display defective brain vessel formation resulting …

Background: New evidence suggests that matrix metalloproteinases (MMPs) may facilitate
angiogenesis as well as function to generate angiogenesis inhibitors. In this study, the …

Hemodynamic forces play a critical role in atherogenesis, as evidenced by the focal pattern
of development of atherosclerotic lesions. Whereas disturbed flow in the branches and …

Wild‐type mouse brain endothelial (bEND) cells transformed with the polyoma virus middle‐
T proliferate rapidly in culture and form hemangiomas in mice. These cells express high …

After infection with Borrelia burgdorferi, humans and mice under certain conditions develop
arthritis. Initiation of inflammation is dependent on the migration of innate immune cells to …

本文旨在对比研究二维平面与三维立体培养模式下, 内皮细胞和心脏组织形态学的差异.
采用胶内, 胶上, 三明治模式, 玻片培养小室模型等多种Ⅰ 型胶原立体培养模型 …

A readily obtainable in vitro paradigm of the blood-brain barrier (BBB) would offer
considerable benefits. Towards this end, we described a novel method for purifying murine …