Biological significance of isoaspartate and its repair system
T Shimizu, Y Matsuoka, T Shirasawa - … and Pharmaceutical Bulletin, 2005 - jstage.jst.go.jp
Isomerization of L-aspartate and deamidation of L-asparagine in proteins or peptides
dominantly give rise to L-isoaspartate by a non-enzymatic reaction via succinimide as a …
dominantly give rise to L-isoaspartate by a non-enzymatic reaction via succinimide as a …
Deamidation: Differentiation of aspartyl from isoaspartyl products in peptides by electron capture dissociation
JJ Cournoyer, JL Pittman, VB Ivleva, E Fallows… - Protein …, 2005 - Wiley Online Library
Deamidation of asparaginyl and isomerization of aspartyl residues in proteins proceed
through a succinimide intermediate producing a mixture of aspartyl and isoaspartyl residues …
through a succinimide intermediate producing a mixture of aspartyl and isoaspartyl residues …
Effects of sucrose and mannitol on asparagine deamidation rates of model peptides in solution and in the solid state
B Li, MH O'Meara, JW Lubach, RL Schowen… - Journal of …, 2005 - Elsevier
Asparagine (Asn) degradation kinetics in two model peptides, Gly-Gln-Asn-Gly-Gly
(GQNGG) and Val-Tyr-Pro-Asn-Gly-Ala (VYPNGA), were studied at 50° C in pH 7 buffer …
(GQNGG) and Val-Tyr-Pro-Asn-Gly-Ala (VYPNGA), were studied at 50° C in pH 7 buffer …
Deamidation and disulfide bridge formation in human calbindin D28k with effects on calcium binding
C Vanbelle, F Halgand, T Cedervall, E Thulin… - Protein …, 2005 - Wiley Online Library
Calbindin D28k (calbindin) is a cytoplasmic protein expressed in the central nervous system,
which is implied in Ca2+ homeostasis and enzyme regulation. A combination of biochemical …
which is implied in Ca2+ homeostasis and enzyme regulation. A combination of biochemical …
Asparaginyl deamidation in two glutamate dehydrogenase isoenzymes from Saccharomyces cerevisiae
The non-enzymatic deamidation of asparaginyl residues is a major source of spontaneous
damage of several proteins under physiological conditions. In many cases, deamidation and …
damage of several proteins under physiological conditions. In many cases, deamidation and …
Spontaneous chemical reversion of an active site mutation: deamidation of an asparagine residue replacing the catalytic aspartic acid of glutamate dehydrogenase
A mutant (D165N) of clostridial glutamate dehydrogenase (GDH) in which the catalytic Asp
is replaced by Asn surprisingly showed a residual 2% of wild-type activity when purified after …
is replaced by Asn surprisingly showed a residual 2% of wild-type activity when purified after …
[图书][B] Mechanistic studies of dephosphorylation for bacterial chemotaxis response regulator CheY
DJ Webre - 2005 - search.proquest.com
Post-translational modifications of proteins by phosphorylation and methylation are
employed to transduce information in living organisms. Enteric bacteria such as Escherichia …
employed to transduce information in living organisms. Enteric bacteria such as Escherichia …
[图书][B] Proteomics methods for detection of modified peptides
BT Hansen - 2005 - search.proquest.com
The recent emergence of the field of proteomics has been driven by advances in mass
spectrometry methods and instrumentation. Due to the large amount of data generated …
spectrometry methods and instrumentation. Due to the large amount of data generated …
[引用][C] D-Amino acid biosystem. Biological significance of isoaspartate and its repair system
T Shimizu, Y Matsuoka, T Shirasawa - Biol Pharm Bull, 2005