The feasibility and limits in performing tomographic bioluminescence imaging with a
combined optical-PET (OPET) system were explored by simulating its image formation …

Recently there has been a strong demand to protect human skin against negative effects of
the UV solar light. This problem is interesting due to the increased frequency of human …

Computer simulation is used to facilitate the design of fiber-probe geometries that enable
enhanced detection of optical signals arising from specific tissue depths. Obtaining …

The standard diffusion approximation (SDA) to the Boltzmann transport equation (BTE) is
commonly used to describe radiative transport for biomedical applications of frequency …

Abstract Elastic Scattering Spectroscopy is a promising in vivo technique for estimating the
size of nuclei in epithelial tissues. Since increased nuclear size is a major morphopathologic …

Optical diagnostic techniques have the potential to improve early detection of pre-cancerous
changes in tissues. These techniques can be implemented in real time without the need for …

This dissertation presents the results of an investigation into experimental, computational,
and analytical methodologies for diagnosing breast cancer using fluorescence and diffuse …

We have developed and validated analytic and computational radiative transport models to
address both forward and inverse problems of light transport applicable on millimeter length …