OBJECTIVE: A primary behavioral pathology in drug addiction is the overpowering
motivational strength and decreased ability to control the desire to obtain drugs. In this …

The discovery that the adult mammalian brain creates new neurons from pools of stemlike
cells was a breakthrough in neuroscience. Interestingly, this particular new form of structural …

Drug addiction is a brain disorder caused by the repetitive use of various chemicals which
alter normal functioning of the central nervous system with consequent behavioral …

OBJECTIVE: The authors examined the separate and combined effects of
methamphetamine dependence and HIV infection on brain morphology. METHOD …

Neonatal ventral hippocampal (nVH) lesions in rats result in adult onset of a number of
behavioral and cognitive abnormalities analogous to those seen in schizophrenia, including …

Rationale There is converging evidence for impairments in decision-making in chronic
substance users. In the light of findings that substance abuse is associated with disruptions …

In this book Sami Timimi, a consultant child and adolescent psychiatrist, goes to the heart of
the problem and challenges contemporary conceptualisations of children and child …

We studied the long-term effects of amphetamine self-administration experience (or sucrose
reward training) on dendritic morphology (spine density) in nucleus accumbens (Nacc) …

Recent reports suggest that nicotine withdrawal symptoms are common among adolescents
after a few weeks of intermittent tobacco use. No current model of nicotine dependence had …

Rationale Repeated exposure to psychomotor stimulants can lead to sensitization to their
effects, and sensitization has been implicated in the pathophysiology of schizophrenia and …