Non-classical protein secretion in bacteria

JD Bendtsen, L Kiemer, A Fausbøll, S Brunak - BMC microbiology, 2005 - Springer
Background We present an overview of bacterial non-classical secretion and a prediction
method for identification of proteins following signal peptide independent secretion …

Evidence of a large novel gene pool associated with prokaryotic genomic islands

WWL Hsiao, K Ung, D Aeschliman, J Bryan… - PLoS …, 2005 - journals.plos.org
Microbial genes that are “novel”(no detectable homologs in other species) have become of
increasing interest as environmental sampling suggests that there are many more such …

LOCSVMPSI: a web server for subcellular localization of eukaryotic proteins using SVM and profile of PSI-BLAST

D Xie, A Li, M Wang, Z Fan, H Feng - Nucleic acids research, 2005 - academic.oup.com
Subcellular location of a protein is one of the key functional characters as proteins must be
localized correctly at the subcellular level to have normal biological function. In this paper, a …

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion …

S Lewenza, JL Gardy, FSL Brinkman… - Genome …, 2005 - genome.cshlp.org
The Gram-negative pathogen Pseudomonas aeruginosa encodes multiple protein export
systems, the substrates of which contain export signals such as N-terminal signal peptides …

An SVM-based system for predicting protein subnuclear localizations

Z Lei, Y Dai - BMC bioinformatics, 2005 - Springer
Background The large gap between the number of protein sequences in databases and the
number of functionally characterized proteins calls for the development of a fast …

TMB-Hunt: an amino acid composition based method to screen proteomes for beta-barrel transmembrane proteins

AG Garrow, A Agnew, DR Westhead - BMC bioinformatics, 2005 - Springer
Background Beta-barrel transmembrane (bbtm) proteins are a functionally important and
diverse group of proteins expressed in the outer membranes of bacteria (both gram negative …

Assessing the precision of high-throughput computational and laboratory approaches for the genome-wide identification of protein subcellular localization in bacteria

S Rey, JL Gardy, FSL Brinkman - BMC genomics, 2005 - Springer
Background Identification of a bacterial protein's subcellular localization (SCL) is important
for genome annotation, function prediction and drug or vaccine target identification …

Proteomic Analysis of the Outer Membrane of Anabaena sp. Strain PCC 7120

S Moslavac, R Bredemeier, O Mirus… - Journal of proteome …, 2005 - ACS Publications
Anabaena is a model to analyze the evolutionary development of plastids, cell
differentiation, and the regulation of nitrogen fixation. Thereby, the outer membrane …

Francisella tularensis Proteome:  Low Levels of ASB-14 Facilitate the Visualization of Membrane Proteins in Total Protein Extracts

SM Twine, NCS Mykytczuk, M Petit… - Journal of proteome …, 2005 - ACS Publications
Proteomic analysis of bacterial pathogens isolated from in vivo sources, such as infected
tissues, provides many challenges not the least of which is the limited quantity of sample …

Identification of a copper‐repressible C‐type heme protein of Methylococcus capsulatus (Bath) A member of a novel group of the bacterial di‐heme cytochrome c …

OA Karlsen, L Kindingstad, SM Angelskår… - The FEBS …, 2005 - Wiley Online Library
Genomic sequencing of the methanotrophic bacterium, Methylococcus capsulatus (Bath),
revealed an open reading frame (MCA2590) immediately upstream of the previously …