Pathogenesis of myelofibrosis with myeloid metaplasia
A Tefferi - Journal of Clinical Oncology, 2005 - ascopubs.org
The primary disease process in myelofibrosis with myeloid metaplasia (MMM) is clonal
myeloproliferation with varying degrees of phenotypic differentiation. This is …
myeloproliferation with varying degrees of phenotypic differentiation. This is …
Leukemic transformation in myelofibrosis with myeloid metaplasia: a single-institution experience with 91 cases
RA Mesa, CY Li, RP Ketterling, GS Schroeder… - Blood, 2005 - ashpublications.org
Among 2333 consecutive patients with myelofibrosis with myeloid metaplasia (MMM) seen
at our institution, 91 fulfilled the World Health Organization (WHO) criteria for leukemic …
at our institution, 91 fulfilled the World Health Organization (WHO) criteria for leukemic …
Essential thrombocythaemia: challenges and evidence‐based management
CN Harrison - British journal of haematology, 2005 - Wiley Online Library
Essential thrombocythaemia was first described over 70 years ago. This condition is
dominated by thrombotic and haemorrhagic complications and, in the long‐term, by risk of …
dominated by thrombotic and haemorrhagic complications and, in the long‐term, by risk of …
Pilot study of reduced‐intensity conditioning followed by allogeneic stem cell transplantation from related and unrelated donors in patients with myelofibrosis
N Kröger, T Zabelina, H Schieder… - British journal of …, 2005 - Wiley Online Library
A prospective pilot study was performed to evaluate the effect of reduced‐intensity
conditioning with busulphan (10 mg/kg), fludarabine (180 mg/qm) and anti‐thymocyte …
conditioning with busulphan (10 mg/kg), fludarabine (180 mg/qm) and anti‐thymocyte …
Essential thrombocythemia
G Finazzi, C Harrison - Seminars in hematology, 2005 - Elsevier
Significant progress in our understanding of the molecular pathogenesis of essential
thrombocythemia (ET) and the other Philadelphia (Ph) chromosome–negative …
thrombocythemia (ET) and the other Philadelphia (Ph) chromosome–negative …
Modern management of myelofibrosis
F Cervantes - British journal of haematology, 2005 - Wiley Online Library
The conventional treatment of myelofibrosis involves a wait‐and‐see approach for
asymptomatic patients, oral chemotherapy for the hyperproliferative forms of the disease …
asymptomatic patients, oral chemotherapy for the hyperproliferative forms of the disease …
Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: a cohort study
H Gisslinger, M Mullner, I Pabinger… - …, 2005 - haematologica.org
The association between a prothrombin mutation and the risk of thrombosis was analyzed in
214 patients with polycythemia vera or essential thrombocythemia. The rate for venous …
214 patients with polycythemia vera or essential thrombocythemia. The rate for venous …
Myelofibrosis with myeloid metaplasia: diagnosis, prognostic factors, and staging
F Cervantes, G Barosi - Seminars in oncology, 2005 - Elsevier
Myelofibrosis with myeloid metaplasia (MMM) is an infrequent disease usually affecting
elderly people. Due to the lack of a specific marker for MMM, efforts are being made to refine …
elderly people. Due to the lack of a specific marker for MMM, efforts are being made to refine …
Detection of Aberrant Gene Expression in CD34+ Hematopoietic Stem Cells from Patients with Agnogenic Myeloid Metaplasia Using Oligonucleotide Microarrays
LC Jones, A Tefferi, PT Vuong, JC Desmond… - Stem Cells, 2005 - academic.oup.com
Agnogenic myeloid metaplasia (AMM) is a clonal stem cell disorder that leads to ineffective
hematopoiesis, bone marrow fibrosis, and extramedullary hematopoiesis. The molecular …
hematopoiesis, bone marrow fibrosis, and extramedullary hematopoiesis. The molecular …
Clinical correlation of bone marrow microvessel density in essential thrombocythemia
K Panteli, N Zagorianakou, NJ Agnantis… - Acta …, 2005 - karger.com
The aim of this study was to investigate the prognostic relevance of angiogenesis expressed
as bone marrow microvessel density (MVD) in 40 patients with essential thrombocythemia …
as bone marrow microvessel density (MVD) in 40 patients with essential thrombocythemia …