Response to psychopharmacologic drugs is genetically complex, results from an interplay of
multiple genomic variations with environmental influences, and depends on the structure or …

The basis of suicidal behavior (SB) is complex and multifactorial. Numerous risk factors have
been identified. Epidemiological genetics studies (family studies, twin studies, adoption …

Context Polymorphisms in the promoter region of the serotonin transporter gene (5-
HTTLPR) influence transcription and may play a role in the pathogenesis and course of …

Pharmacogenetic factors operate at pharmacokinetic as well as pharmacodynamic levels—
the two components of the dose–response curve of a drug. Polymorphisms in drug …

While antidepressants have been demonstrated to be a safe and effective treatment for
unipolar major depressive disorder (MDD) in adults, the use of antidepressants to treat …

Abstract Background and Objective: Obstructive sleep apnea syndrome (OSAS) is a
common condition characterized by repetitive pharyngeal collapse during sleep and …

Rationale Serotonergic mechanisms are thought to play an important role in the regulation
of mood, motor activity and sleep patterns. Serotonin reuptake is controlled by the serotonin …

Psychotropic drugs, like antipsychotics, antidepressants, mood stabilizers and anxiolytics,
are effective for alleviation of certain psychiatric symptoms, however, the adverse-effects …

I. INTRODUCTION The use of psychiatric medication has transcended geographic, cultural,
and ethnic boundaries during the past several decades. Within a few years of their …

Suicide persists as a major public health problem in all industrialized countries. More than
90% of people who commit suicide suffered from a psychiatric disorder, mostly a mood …