Melatonin, dubbed the hormone of darkness, is known to regulate a wide variety of
physiological processes in mammals. This review describes well-defined functional …

Melatonin, the main secretory product of the pineal gland, is known to collaborate against
oxidative stress within cells, but its mechanism of action in terms of stimulating antioxidant …

Ramelteon (TAK-375) is a novel melatonin receptor agonist currently under investigation for
the treatment of insomnia. This study describes the neurochemical and receptor binding …

The pineal product melatonin has remarkable antioxidant properties. It scavenges hydroxyl,
carbonate and various organic radicals, peroxynitrite and other reactive nitrogen species …

In this article, we review the experimental data supporting an oncostatic role of melatonin on
hormone‐dependent mammary tumors. Beginning with the evidence on the role of …

Besides the hypothalamus and pituitary, melatonin action at the testicular level has been
recently suggested. Therefore, we investigated in the Syrian hamster, a well-characterized …

The high incidence of age-related diseases in the increasing population of elderly people
has stimulated interest in the search for protective agents that have the capability of …

Circadian rhythmicity is evident in a wide range of physiological systems including the
reproductive axis. The recent discoveries of rhythmic clock gene expression in peripheral …

Melatonin plays a critical role in a variety of mammalian reproductive processes not only
acting on the central nervous system but also behaving as a peripheral physiologic …

Osteogenesis in the teleost was morphologically observed using regenerating scales of
goldfish. Histological observations indicated that osteoblasts around the regenerating scales …