Poly (ADP-ribosyl) ation in asthma and other lung diseases

L Virág - Pharmacological Research, 2005 - Elsevier
Inhibition of poly (ADP-ribosyl) ation in oxidative stress-related pathologies has recently
emerged as a very effective anti-inflammatory intervention in animal models of arthritis …

Tankyrase-1 overexpression reduces genotoxin-induced cell death by inhibiting PARP1

TYJ Yeh, JI Sbodio, MTA Nguyen, TN Meyer… - Molecular and cellular …, 2005 - Springer
Poly (ADP-ribose) polymerases or PARPs are a family of NAD+-dependent enzymes that
modify themselves and other substrate proteins with ADP-ribose polymers. The founding …

Mice lacking the 110-kD isoform of poly (ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury

NSA Patel, U Cortes, R Di Poala… - Journal of the …, 2005 - journals.lww.com
The role of poly (ADP-ribose)(PAR) glycohydrolase (PARG) in the pathophysiology of renal
ischemia/reperfusion (I/R) injury is not known. Poly (ADP-ribosyl) ation is rapidly stimulated …

PARP-1 inhibition to treat cancer, ischemia, inflammation

G Graziani, F Battaini, J Zhang - Pharmacological research, 2005 - art.torvergata.it
ag 14699; benzamide; ino 1001; nicotinamide adenine dinucleotide adenosine diphosphate
ribosyltransferase; nicotinamide adenine dinucleotide adenosine diphosphate …

Role of poly-(ADP-ribose) polymerase in transplant acute tubular necrosis and its relationship with delayed renal function

F O'Valle, MC Benıtez, M Gómez-Morales… - Transplantation …, 2005 - Elsevier
The enzyme poly (ADP-ribose) polymerase (PARP-1) participates in the repair of DNA
damaged by genotoxic agents such as oxygen-derived free radicals. If the allograft suffers …

[PDF][PDF] 辐射诱导的DNA 修复与细胞凋亡的ATP 调控

周清明, 张红, 党秉荣, 李文建, 刘兵, 闵凤玲, 段昕… - 原子核物理评论, 2005 - npr.ac.cn
辐射诱导的DNA修复与细胞凋亡的ATP调控 Page 1 第22卷第2期 2005年6月 原子核物理评论
NuclearPhysicsReview Vol,22,NO.2 JUric,2005 文章编号:1007—4627(2005)02-0225-04 …

The role of poly (adenosine 5′-diphosphate-ribose) polymerase in the response of pituitary tumor cells to reactive oxygen species

CJ Newton, D Bilko, M Tichomirowa, U Renner… - …, 2005 - academic.oup.com
As an enzyme implicated in the stress response, we investigated poly (ADP-ribose)
polymerase (PARP) in the response of GH3 rat pituitary tumor cells to oxidants. These cells …

[PDF][PDF] Mechanism of liver cell injury

M Kresse - kops.uni-konstanz.de
My special thanks go to my supervisor Prof. Wendel. He did not only provide excellent
working facilities and a generous financing of the project, but also enabled this study by his …