Sex steroids, cardiovascular disease, and hypertension: unanswered questions and some speculations

JF Reckelhoff - Hypertension, 2005 - Am Heart Assoc
menopause years before the start of the HRT. Thus, it is possible that starting HRT in women
during perimenopause may prove more beneficial. 11 In addition, the many previous studies …

Changes in renal hemodynamics and structure in the aging kidney; sexual dimorphism and the nitric oxide system

C Baylis - Experimental gerontology, 2005 - Elsevier
With advancing age the kidney shows both functional declines (falls in GFR) and
development of structural damage. In most individuals this occurs slowly and does not lead …

Sex differences in the development of angiotensin II-induced hypertension in conscious mice

B Xue, J Pamidimukkala, M Hay - American Journal of …, 2005 - journals.physiology.org
Sex has an important influence on blood pressure (BP) regulation. There is increasing
evidence that sex hormones interfere with the renin-angiotensin system. Thus the purpose of …

Progesterone antagonizes the vasoprotective effect of estrogen on antioxidant enzyme expression and function

K Wassmann, S Wassmann, G Nickenig - Circulation research, 2005 - Am Heart Assoc
Oxidative stress plays an important role in the pathogenesis of atherosclerosis and can be
effectively influenced by radical scavenging enzymes. Estrogens exert antioxidative effects …

Sexual dimorphism in angiotensin II-induced hypertension and vascular alterations

R Tatchum-Talom, KM Eyster… - Canadian journal of …, 2005 - cdnsciencepub.com
Les différences liées au sexe dans le degré d'hypertension ont été décrites dans plusieurs
modèles animaux expérimentaux d'hypertension. Toutefois, l'influence du sexe sur …

Estrogen reduces angiotensin II-induced acceleration of senescence in endothelial progenitor cells

T Imanishi, T Hano, I Nishio - Hypertension research, 2005 - nature.com
The interaction among estrogen, angiotensin II (Ang II), and oxidative stress in endothelial
progenitor cells (EPCs) remains unknown. We therefore investigated the potential effect of …

Sex Difference in Vascular Injury and the Vasoprotective Effect of Valsartan Are Related to Differential AT2 Receptor Expression

M Okumura, M Iwai, A Ide, M Mogi, M Ito… - Hypertension, 2005 - Am Heart Assoc
The angiotensin II type 2 (AT2) receptor is upregulated in pathological conditions such as
vascular injury and exerts antagonistic effects against AT1 receptor–mediated actions. We …

Angiotensin II regulation of ovine fetoplacental artery endothelial functions: interactions with nitric oxide

J Zheng, IM Bird, DB Chen… - The Journal of …, 2005 - Wiley Online Library
During normal pregnancy, elevated angiotensin II (Ang II) concentrations in the maternal
and fetal circulations are associated with dramatic increases in placental angiogenesis and …

Aetiology and management of male erectile dysfunction and female sexual dysfunction in patients with cardiovascular disease

SL Archer, FS Gragasin, L Webster, D Bochinski… - Drugs & aging, 2005 - Springer
The historical basis for understanding erectile function as a neurovascular phenomenon and
the advance from fanciful to effective treatment of erectile dysfunction (ED) are reviewed …

Management of the menopausal disturbances and oxidative stress

F Pansini, G Mollica… - Current pharmaceutical …, 2005 - ingentaconnect.com
Women frequently seek gynaecologic medical advice at menopause and require
pharmacologic interventions to control subjective vasomotor complaints and to prevent late …