The mucosal immune system in the female reproductive tract (FRT) has evolved to meet the
unique requirements of dealing with sexually transmitted bacterial and viral pathogens …

The continued presence of bacterial and viral antigens in the lumen of the vagina coupled
with the periodic presence of antigens in the lumena of the upper reproductive tract provide …

OBJECTIVE: HOXA10, expressed in endometrium, plays an important role in uterine
receptivity at the time of implantation. In the endometrium of women with endometriosis, its …

Developmental exposure to estrogenic chemicals induces morphological, functional, and
behavioral anomalies associated with reproduction. Humans are routinely exposed to …

The uterus is an essential organ for reproduction in mammals. Despite the importance of the
uterus for the fertility and health of women and their offspring, relatively little is known about …

BACKGROUND: A novel organotypic culture system was established for modelling the
hormonal responses of the normal human endometrium in vitro. METHODS: Endometrial …

Transforming growth factor (TGF)-β1 is a potent inhibitor of mammary epithelial proliferation.
In human breast, estrogen receptor (ER)-α cells rarely co-localize with markers of …

The mammalian cell cycle is regulated by the cyclin/cyclin-dependent kinase (CDK)
phosphorylation of the retinoblastoma (pRB) family of proteins. Cyclin D1 with its CDK4/6 …

Although 17β-estradiol (E2) is recognized as a potent hair growth modulator, our knowledge
of estrogen function, signaling, and target genes in hair biology is still very limited. Between …

Apart from distinguishing the in vivo effects of progesterone (P) from those of estrogen (E),
the progesterone receptor knockout (PRKO) mouse has furnished unprecedented access to …