Role of resistin in obesity, insulin resistance and Type II diabetes

CM Kusminski, PG Mcternan, S Kumar - Clinical science, 2005 - portlandpress.com
Resistin is a member of a class of cysteine-rich proteins collectively termed resistin-like
molecules. Resistin has been implicated in the pathogenesis of obesity-mediated insulin …

Adiponectin: a relevant player in PPARγ-agonist-mediated improvements in hepatic insulin sensitivity?

M Bouskila, UB Pajvani, PE Scherer - International journal of obesity, 2005 - nature.com
The potent insulin-sensitizing effects of peroxisome proliferator-activated receptor γ (PPARγ)
agonists are well established. However, it is still a matter of intense debate as to which …

Peroxisome proliferator–activated receptor (PPAR) α activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue …

A Tsuchida, T Yamauchi, S Takekawa, Y Hada, Y Ito… - Diabetes, 2005 - Am Diabetes Assoc
We examined the effects of activation of peroxisome proliferator–activated receptor (PPAR)
α, PPARγ, and both of them in combination in obese diabetic KKAy mice and investigated …

Serum resistin levels of obese and lean children and adolescents: biochemical analysis and clinical relevance

M Gerber, A Boettner, B Seidel… - The Journal of …, 2005 - academic.oup.com
Objective: It was hypothesized that resistin links obesity with diabetes, but this has not been
studied in children and adolescents to date. Patients: We determined serum resistin levels of …

Effects of adipocyte-derived cytokines on endothelial functions: implication of vascular disease

P Kougias, H Chai, PH Lin, Q Yao, AB Lumsden… - Journal of Surgical …, 2005 - Elsevier
Adipose tissue has recently emerged as an active endocrine organ that secretes a variety of
metabolically important substances, collectively called adipocytokines or adipokines. In this …

Effect of PPAR-α and-γ agonist on the expression of visfatin, adiponectin, and TNF-α in visceral fat of OLETF rats

KC Choi, OH Ryu, KW Lee, HY Kim, JA Seo… - Biochemical and …, 2005 - Elsevier
A variety of adipocytokines and peptides secreted from adipocytes have been considered to
play a crucial role in obesity, insulin resistance, and type 2 diabetes. Recently, visfatin, a …

The effect of PPARγ ligands on the adipose tissue in insulin resistance

A Hammarstedt, CX Andersson, VR Sopasakis… - … and Essential Fatty …, 2005 - Elsevier
Insulin resistance is frequently accompanied by obesity and both obesity and type 2
diabetes are associated with a mild chronic inflammation. Elevated levels of various …

Adipocytokines: fat-derived humoral mediators of metabolic homeostasis

H Staiger, HU Häring - Experimental and clinical endocrinology …, 2005 - thieme-connect.com
The metabolic syndrome currently reaches epidemic proportions in the Western
industrialized world. Its hallmarks obesity, type 2 diabetes mellitus, and atherosclerosis are …

Circulating resistin in lean, obese, and insulin-resistant mouse models: lack of association with insulinemia and glycemia

JH Lee, JW Bullen Jr, VL Stoyneva… - American Journal of …, 2005 - journals.physiology.org
Resistin is an adipocyte-secreted hormone proposed to link obesity with insulin resistance
and diabetes, but no previous study has performed a joint quantitative evaluation of white …

Adiponectina: un nuevo nexo entre obesidad, resistencia a la insulina y enfermedad cardiovascular

X Palomer, A Pérez, F Blanco-Vaca - Medicina clínica, 2005 - Elsevier
La adiponectina es una adipocitocina secretada por los adipocitos que regula el
metabolismo energético del organismo, ya que estimula la oxidación de ácidos grasos …