In eukaryotes, glycosylated proteins are ubiquitous components of extracellular matrices
and cellular surfaces. Their oligosaccharide moieties are implicated in a wide range of cell …

One of the first hurdles to be negotiated in the postgenomic era involves the description of
the entire protein content of the cell, the proteome. Such efforts are presently complicated by …

In this study, we tested the contribution of flagellar motility, flagellin structure, and its
glycosylation in Pseudomonas aeruginosa using genetically defined flagellar mutants. All …

Protein O-mannosylation is an essential and evolutionarily conserved post-translational
modification among eukaryotes. This form of protein modification is also described in …

The flagellum of Methanococcus voltae is composed of four structural flagellin proteins FlaA,
FlaB1, FlaB2, and FlaB3. These proteins possess a total of 15 potential N-linked sequons …

The Toll-like receptor 5 (TLR5) binding site has been predicted to be in the N terminus of the
flagellin molecule. In order to better define the interaction between the N-terminal amino …

The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of nosocomial
pneumonia. Among its virulence factors, the type IV pili of P. aeruginosa strain 1244 contain …

The goal of this project was to develop a vaccination strategy that would enhance the
protective humoral immune response against the flagellin protein of Pseudomonas …