M2, M3, and M4 receptor subtypes contribute to muscarinic potentiation of GABAergic inputs to spinal dorsal horn neurons

HM Zhang, DP Li, SR Chen, HL Pan - Journal of Pharmacology and …, 2005 - ASPET
The spinal cholinergic system and muscarinic receptors are important for regulation of
nociception. Activation of spinal muscarinic receptors produces analgesia and inhibits …

Synaptic input of rat spinal lamina I projection and unidentified neurones in vitro

A Dahlhaus, R Ruscheweyh… - The Journal of …, 2005 - Wiley Online Library
Spinal lamina I projection neurones that transmit nociceptive information to the brain play a
pivotal role in hyperalgesia in various animal models of inflammatory and neuropathic pain …

α2-Adrenoceptor Activation by Clonidine Enhances Stimulation-evoked Acetylcholine Release from Spinal Cord Tissue after Nerve Ligation in Rats

H Obata, X Li, JC Eisenach - The Journal of the American Society of …, 2005 - pubs.asahq.org
Background Spinally administered clonidine produces analgesia via alpha2-adrenergic
receptors. The analgesic potency of clonidine and its dependency on muscarinic …

Involvement of spinal serotonin receptors in the regulation of intraspinal acetylcholine release

M Kommalage, AU Höglund - European journal of pharmacology, 2005 - Elsevier
Stimulation of spinal serotonin (5-HT) receptors results in analgesia and release of
acetylcholine. We investigated the involvement of 5-HT1, 5-HT2, and 5-HT3 receptor …

M3-like muscarinic receptors mediate Ca2+ influx in rat mesencephalic GABAergic neurones through a protein kinase C-dependent mechanism

FJ Michel, GD Fortin, P Martel, J Yeomans… - …, 2005 - Elsevier
GABAergic neurones in the mesencephalon are important regulators of dopamine
neurones. Cholinergic projections from mesopontine nuclei preferentially synapse onto …

Involvement of spinal GABA receptors in the regulation of intraspinal acetylcholine release

M Kommalage, AU Höglund - European journal of pharmacology, 2005 - Elsevier
It has been shown that analgesics such as morphine, lidocaine and clonidine increase the
release of spinal acetylcholine. Acetylcholine may therefore play an important role in the …

Acetylcholine in Spinal Pain Modulation: An in vivo Study in the Rat

K Abelson - 2005 - diva-portal.org
Abstract Abelson, K. 2005. Acetylcholine in Spinal Pain Modulation. An in vivo Study in the
Rat. Acta Universitatis Upsaliensis. Digital Comprehensive Summaries of Uppsala …