Ertapenem: review of a new carbapenem

GG Zhanel, C Johanson, JM Embil… - Expert review of anti …, 2005 - Taylor & Francis
The carbapenems are β-lactam-type antibiotics with an exceptionally broad spectrum of
activity. Ertapenem is a new carbapenem developed to address the pharmacokinetic …

Ertapenem: a review of its use in the treatment of bacterial infections

GM Keating, CM Perry - Drugs, 2005 - Springer
Summary Abstract The Group 1, 1β-methyl carbapenem ertapenem (Invanz®) is approved
for parenteral use in patients with complicated intra-abdominal infection (cIAI), community …

Acquisition of resistant bowel flora during a double-blind randomized clinical trial of ertapenem versus piperacillin-tazobactam therapy for intraabdominal infections

MJ DiNubile, JW Chow, V Satishchandran… - Antimicrobial agents …, 2005 - Am Soc Microbiol
Bowel colonization with resistant bacteria can develop in patients receiving broad-spectrum
antimicrobial therapy. We compared the impact of two antimicrobial regimens often used to …

Safety of newer parenteral antibiotics

GE Stein - Clinical infectious diseases, 2005 - academic.oup.com
Several parenteral antimicrobials have been introduced into clinical practice over the course
of the last decade. Some of these agents (eg, linezolid, daptomycin, and tigecycline) are …

Penetration of ertapenem into different pulmonary compartments of patients undergoing lung surgery

O Burkhardt, J Majcher‐Peszynska… - The Journal of …, 2005 - Wiley Online Library
Ertapenem is approved for the treatment of community‐acquired pneumonia (CAP), but its in
vivo penetration into lung tissue (LT), epithelial lining fluid (ELF), and alveolar cells (AC) is …