'Protein Peeling': an approach for splitting a 3D protein structure into compact fragments
JC Gelly, AG De Brevern, S Hazout - Bioinformatics, 2006 - academic.oup.com
Motivation: The object of this study is to propose a new method to identify small compact
units that compose protein three-dimensional structures. These fragments, called 'protein …
units that compose protein three-dimensional structures. These fragments, called 'protein …
A folding inhibitor of the HIV‐1 protease
RA Broglia, D Provasi, F Vasile… - Proteins: Structure …, 2006 - Wiley Online Library
Because the human immunodeficiency virus type 1 protease (HIV-1-PR) is an essential
enzyme in the viral life cycle, its inhibition can control AIDS. The folding of singledomain …
enzyme in the viral life cycle, its inhibition can control AIDS. The folding of singledomain …
Sequence of events in folding mechanism: beyond the Gō model
Simplified Gō models, where only native contacts interact favorably, have proven useful to
characterize some aspects of the folding of small proteins. The success of these models is …
characterize some aspects of the folding of small proteins. The success of these models is …
The generic nature of protein folding and misfolding
CM Dobson - … , Aggregation, and Conformational Diseases: Part A …, 2006 - Springer
The ability of proteins to fold to their functional states is an astonishing example of the power
of biological evolution at the molecular level. Despite the large number of different native …
of biological evolution at the molecular level. Despite the large number of different native …
Thermodynamic features characterizing good and bad folding sequences obtained using a simplified off-lattice protein model
A Amatori, J Ferkinghoff-Borg, G Tiana… - Physical Review E …, 2006 - APS
The thermodynamics of the small SH3 protein domain is studied by means of a simplified
model where each beadlike amino acid interacts with the others through a contact potential …
model where each beadlike amino acid interacts with the others through a contact potential …
Theexperimentalsurveyofprotein-folding energy landscapes
M Oliveberg, PG Wolynes - Q. Re - cambridge.org
We review what has been learned about the protein-folding problem from experimental
kinetic studies. These studies reveal patterns of both great richness and surprising simplicity …
kinetic studies. These studies reveal patterns of both great richness and surprising simplicity …
Hierarchy of events in protein folding: beyond the Go model
Simplified Go models, where only native contacts interact favorably, have proven useful to
characterize some aspects of the folding of small proteins. The success of these models is …
characterize some aspects of the folding of small proteins. The success of these models is …