A modified α-galactosyl ceramide for staining and stimulating natural killer T cells
Y Liu, RD Goff, D Zhou, J Mattner, BA Sullivan… - Journal of …, 2006 - Elsevier
CD1d presentation of α-galactosyl ceramides to natural killer T cells has been a focal point
of the study of regulatory T cells. KRN7000, an α-galactosyl ceramide originally generated …
of the study of regulatory T cells. KRN7000, an α-galactosyl ceramide originally generated …
TLR gateways to CD1 function
DB Moody - Nature immunology, 2006 - nature.com
CD1-restricted T cells can be activated by diverse lipids derived from mammals, bacteria
and protozoa. Certain lipids function as antigens, which bind to CD1 proteins and contact T …
and protozoa. Certain lipids function as antigens, which bind to CD1 proteins and contact T …
Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases
SD Gadola, JD Silk, A Jeans, PA Illarionov… - The Journal of …, 2006 - rupress.org
Glycolipid ligands for invariant natural killer T cells (i NKT cells) are loaded onto CD1d
molecules in the late endosome/lysosome. Accumulation of glycosphingolipids (GSLs) in …
molecules in the late endosome/lysosome. Accumulation of glycosphingolipids (GSLs) in …
Structure and binding kinetics of three different human CD1d–α-galactosylceramide–specific T cell receptors
SD Gadola, M Koch, J Marles-Wright… - The Journal of …, 2006 - rupress.org
Invariant human TCR Vα24-Jα18+/Vβ11+ NKT cells (iNKT) are restricted by CD1d–α-
glycosylceramides. We analyzed crystal structures and binding characteristics for an iNKT …
glycosylceramides. We analyzed crystal structures and binding characteristics for an iNKT …
The surprising diversity of lipid antigens for CD1‐restricted T cells
DB Moody - Advances in immunology, 2006 - Elsevier
CD1 proteins have been conserved throughout mammalian evolution and function to
present lipid antigens to T cells. Crystal structures of CD1‐lipid complexes show that CD1 …
present lipid antigens to T cells. Crystal structures of CD1‐lipid complexes show that CD1 …
Cutting edge: rapid recovery of NKT cells upon institution of highly active antiretroviral therapy for HIV-1 infection
HJJ Van Der Vliet, MGA Van Vonderen… - The Journal of …, 2006 - journals.aai.org
CD1d-restricted NKT cells play important regulatory roles in various immune responses and
are rapidly and selectively depleted upon infection with HIV-1. The cause of this selective …
are rapidly and selectively depleted upon infection with HIV-1. The cause of this selective …
The complementarity determining region 2 of BV8S2 (Vβ8. 2) contributes to antigen recognition by rat invariant NKT cell TCR
E Pyz, O Naidenko, S Miyake, T Yamamura… - The Journal of …, 2006 - journals.aai.org
Invariant NKT cells (iNKT cells) are characterized by a semi-invariant TCR comprising an
invariant α-chain paired with β-chains with limited BV gene usage which are specific for …
invariant α-chain paired with β-chains with limited BV gene usage which are specific for …
Enhanced ability of peripheral invariant natural killer T cells to produce IL-13 in chronic hepatitis C virus infection
M Inoue, T Kanto, H Miyatake, I Itose, M Miyazaki… - Journal of …, 2006 - Elsevier
BACKGROUND/AIMS: Human invariant natural killer T (iNKT) cells express a TCR Vα24-
JαQ paired with Vβ11 and are activated by a surrogate ligand, α-galactosylceramide …
JαQ paired with Vβ11 and are activated by a surrogate ligand, α-galactosylceramide …
Oxidative folding of conotoxins in immobilized systems
BR Green, G Bulaj - Protein and Peptide Letters, 2006 - ingentaconnect.com
We tested two alternative oxidation strategies to produce conotoxins α-GI and μ-PIIIA. The
peptides were either reversibly immobilized on a solid support and then oxidized, or the …
peptides were either reversibly immobilized on a solid support and then oxidized, or the …
Natural killer T cells and haemopoiesis
A Karadimitris, S Patterson… - British journal of …, 2006 - Wiley Online Library
Invariant natural killer T (iNKT) cells are a small but powerful subset of regulatory T cells
involved in the modulation of a variety of normal and pathological immune responses. In …
involved in the modulation of a variety of normal and pathological immune responses. In …